<p>Counterstaining for α-actinin and c-Kit in EBs exposed to 100 nM STS for 5 h and then cultured for additional 7 days. Area defined by the rectangle indicates clusters of c-Kit/α-actinin<sup>low</sup> cells, and arrow indicates α-actinin<sup>high</sup> cardiomyocytes. 7 days after the indicated treatments, EBs were pulsed for 30 minutes with EdU and then stained for α-actinin (green), c-Kit (red) and EdU (blue). Blue nuclei indicate proliferating cells. Bars represent 100 μm.</p
Background: The possibility of culturing heart cells in order to regenerate damaged tissue is a chal...
<p>(A) Ratios of beating cardiac foci corrected for total EBs plated in 8 independent experiments, a...
Promoting cardiomyocyte proliferation is a promising strategy to regenerate the heart. Yet, so far, ...
<p>(A) GFP expression levels in EBs exposed to vehicle or 100 nM STS +/- Q-VD-OPH (upper panels) and...
Generation of new cardiomyocytes is critical for cardiac repair following myocardial injury, but whi...
<p><b>A,</b> Co-staining of BrdU and cardiac markers (a-actinin) to determine the effect of NCMs co-...
RATIONALE:Biological significance of c-Kit as a cardiac stem cell marker and role(s) of c-Kit+ cells...
<p>(A) Representative images of DNA damage (53BP1 foci) in c-kit-positive stem cells. Arrows and arr...
<p>(<b>A</b>) Flow cytometry analysis of outgrowths cultured for 21 days shows percent of Wt1+ cells...
<p>(A) Treatment of EB cultures with exogenous CS-E, but not C4S, from d0 to d4 significantly decrea...
<p>A. Representative c-kit stained sections 3d after coronary artery ligation and saline or mini-Tyr...
<p>Human c-kit+ CPCs were serum starved for 24 hr and labeled with BrdU in the presence or absence o...
(A-C) Cardiomyocytes were seeded either on glass coverslips (A and ‘Glass’ in C) or 15 kPa PAA gels ...
Human c-kit(+) cardiac progenitor cells (CPCs) are multipotent and may be used for cardiac repair. T...
<p>X-gal stained embryoid bodies show early enrichment in cardiac-MHC-LacZ expressing areas (blue st...
Background: The possibility of culturing heart cells in order to regenerate damaged tissue is a chal...
<p>(A) Ratios of beating cardiac foci corrected for total EBs plated in 8 independent experiments, a...
Promoting cardiomyocyte proliferation is a promising strategy to regenerate the heart. Yet, so far, ...
<p>(A) GFP expression levels in EBs exposed to vehicle or 100 nM STS +/- Q-VD-OPH (upper panels) and...
Generation of new cardiomyocytes is critical for cardiac repair following myocardial injury, but whi...
<p><b>A,</b> Co-staining of BrdU and cardiac markers (a-actinin) to determine the effect of NCMs co-...
RATIONALE:Biological significance of c-Kit as a cardiac stem cell marker and role(s) of c-Kit+ cells...
<p>(A) Representative images of DNA damage (53BP1 foci) in c-kit-positive stem cells. Arrows and arr...
<p>(<b>A</b>) Flow cytometry analysis of outgrowths cultured for 21 days shows percent of Wt1+ cells...
<p>(A) Treatment of EB cultures with exogenous CS-E, but not C4S, from d0 to d4 significantly decrea...
<p>A. Representative c-kit stained sections 3d after coronary artery ligation and saline or mini-Tyr...
<p>Human c-kit+ CPCs were serum starved for 24 hr and labeled with BrdU in the presence or absence o...
(A-C) Cardiomyocytes were seeded either on glass coverslips (A and ‘Glass’ in C) or 15 kPa PAA gels ...
Human c-kit(+) cardiac progenitor cells (CPCs) are multipotent and may be used for cardiac repair. T...
<p>X-gal stained embryoid bodies show early enrichment in cardiac-MHC-LacZ expressing areas (blue st...
Background: The possibility of culturing heart cells in order to regenerate damaged tissue is a chal...
<p>(A) Ratios of beating cardiac foci corrected for total EBs plated in 8 independent experiments, a...
Promoting cardiomyocyte proliferation is a promising strategy to regenerate the heart. Yet, so far, ...