<p>Survival in days ± the standard deviation of male and female transgenic mutant (G59S) human dynactin p150<sup>Glued</sup> mice in different genetic backgrounds. There was no significant difference in survival (p>0.05) between male and female mice in any background. There were significant difference in survival between animals in the different backgrounds (B6 vs. B6/SJL p<0.00001; B6 vs. SJL p<0.00001; B6SJL vs. SJL p<0.00001).</p><p>Survival for mutant (G59S) human dynactin p150<sup>Glued</sup> mice.</p
Effect of genotype at chromosome 18, 25.9 cM on survival. The survival in days is plotted as the mea...
<p><b>(A)</b> Average growth curves from control mice kept under nonSPF conditions indicate evolving...
<p>Wild-type (solid line, n = 381 animals, 8 deaths), <i>Npc1</i> mutants (○, n = 134 animals, 91 de...
<p>Disease onset in days ± the standard deviation of male and female transgenic mutant (G59S) human ...
Survival curves for transgenic C57BL6/J, SJL/J mice and their F2 cross with [A] the G93A human SOD1 ...
<p>(A) Survival curves for C57BL/6 (B6) congenic <i>SOD1<sup>G93A</sup></i> transgenic mice (B6_G93A...
<p>(A) Survival curves for C57BL/6 (B6) congenic <i>SOD1<sup>G93A</sup></i> transgenic female mice (...
<p>Survival is prolonged when the G59S mutant dynactin is placed on the B6 background and decreased ...
<p>Survival curves of βENaC-Tg mice and wild-type (WT) littermates on mixed (C3H/He x C57BL/6), C57B...
<p>Reproduction parameters of <i>Pw1</i> mutant mice are comparable to <i>Pw1</i><sup><i>+/+</i></su...
<p>DFS curves for each strain of <i>MDTG;neu</i> females are shown. The <i>p</i> values were calcula...
a<p>Time to death ± standard deviation in days.</p><p>*Statistical differences were considered signi...
<p>Median survivals are shown in the figure legends in parentheses. <i>dna-pk<sub>cs</sub><sup>−/−</...
<p>(A) Normalized liver weight is significantly increased in male mutant mice (P = 0.008). (B) Absol...
Effect of the genotype at chromosome 17, 43.8 cM on survival. The survival in days is plotted as the...
Effect of genotype at chromosome 18, 25.9 cM on survival. The survival in days is plotted as the mea...
<p><b>(A)</b> Average growth curves from control mice kept under nonSPF conditions indicate evolving...
<p>Wild-type (solid line, n = 381 animals, 8 deaths), <i>Npc1</i> mutants (○, n = 134 animals, 91 de...
<p>Disease onset in days ± the standard deviation of male and female transgenic mutant (G59S) human ...
Survival curves for transgenic C57BL6/J, SJL/J mice and their F2 cross with [A] the G93A human SOD1 ...
<p>(A) Survival curves for C57BL/6 (B6) congenic <i>SOD1<sup>G93A</sup></i> transgenic mice (B6_G93A...
<p>(A) Survival curves for C57BL/6 (B6) congenic <i>SOD1<sup>G93A</sup></i> transgenic female mice (...
<p>Survival is prolonged when the G59S mutant dynactin is placed on the B6 background and decreased ...
<p>Survival curves of βENaC-Tg mice and wild-type (WT) littermates on mixed (C3H/He x C57BL/6), C57B...
<p>Reproduction parameters of <i>Pw1</i> mutant mice are comparable to <i>Pw1</i><sup><i>+/+</i></su...
<p>DFS curves for each strain of <i>MDTG;neu</i> females are shown. The <i>p</i> values were calcula...
a<p>Time to death ± standard deviation in days.</p><p>*Statistical differences were considered signi...
<p>Median survivals are shown in the figure legends in parentheses. <i>dna-pk<sub>cs</sub><sup>−/−</...
<p>(A) Normalized liver weight is significantly increased in male mutant mice (P = 0.008). (B) Absol...
Effect of the genotype at chromosome 17, 43.8 cM on survival. The survival in days is plotted as the...
Effect of genotype at chromosome 18, 25.9 cM on survival. The survival in days is plotted as the mea...
<p><b>(A)</b> Average growth curves from control mice kept under nonSPF conditions indicate evolving...
<p>Wild-type (solid line, n = 381 animals, 8 deaths), <i>Npc1</i> mutants (○, n = 134 animals, 91 de...