SOD1 DJ-1 KO-mice lost weight earlier and faster than SOD1 mice.

<p>A, Weight of female mice. B, Weight of male mice. Disease onset was calculated retrospectively as the day the mouse reached peak body weight. Disease onset was significantly earlier in both male and female SOD1 DJ-1 KO mice as compared to SOD1 mice (C, female mice; D, male mice). Data is presented as averages ± SE. * p<0.05, ** p<0.01. n = SOD1 mice 9F and 9M, SOD1 DJ-1 KO mice 14F and 22M.