Timed data for onset and survival.

<p>Given are parameters for disease onset (A-C), and survival (D) for the SOD-1 (G93A) (n = 17) and SOD-1 (G93A)^PS mice (n = 8). (A) Onset of weight decrease was defined as a drop of 5% of the mouse maximal weight. (B) First manifestation of symptoms that are linked to gait impairment in terms of limbs coordination and overall stance, and (C) time to first manifestation of paresis. (D) End point of the disease, defined as the inability of the mouse to right itself within 30 seconds.