<p>a. Number of cases and controls per gene vary due to exhausted DNA and/or inability to generate pyrosequencing data</p><p>b. Summary statistics with a nonparametric Mann-Whitney test comparing cases and controls for each gene</p><p>Distribution of DNA methylation Index among ten tumor suppressor genes in cervical cancer cases and controls.</p
<p>(<b>A</b>) Probability density function (PDF) distribution for methylation difference between DS ...
<p><b>A.</b> Genes commonly methylated in >95% of all samples.</p><p><b>B.</b> Genes methylated in a...
Background: Epigenetic gene silencing is one of the major causes of carcinogenesis. Its widespread o...
DNA methylation occurs when methyl groups attach to cytosine bases on DNA segments. Previous studies...
<p>Genes are ordered by Mann-Whitney <i>p-value (</i>** p-value<0.0001 and * p-value<0.05). Methylat...
<p>LSIL, low-grade squamous cell intraepithelial lesion; HSIL, high-grade squamous cell intraepithel...
Summary statistics for case/control expression differences in whole blood for genes identified in DN...
<p>(A) Distribution of the percentage methylation levels (shown as <i>Z</i> scores) in all tumors. B...
<p>There is a bimodal distribution of the DNA index with peaks around 1, and close to 2.</p
<p>The genes are ranked by outlier score. Spearman's coefficient was calculated to evaluate DNA meth...
<p>List of the top 10 genes that were hypermethylated in at least 85% of benign and malignant tumor ...
Cervical cancer is the fourth most common cancer affecting women worldwide, with a high incidence an...
Cervical cancer is the fourth most common cancer affecting women worldwide, with a high incidence an...
<p>All 997 genes (circles) that were deregulated in cervical cancer (CC) tumors compared to the cont...
<p>Genomic distribution of probes differentially methylated between leukemic and control samples wit...
<p>(<b>A</b>) Probability density function (PDF) distribution for methylation difference between DS ...
<p><b>A.</b> Genes commonly methylated in >95% of all samples.</p><p><b>B.</b> Genes methylated in a...
Background: Epigenetic gene silencing is one of the major causes of carcinogenesis. Its widespread o...
DNA methylation occurs when methyl groups attach to cytosine bases on DNA segments. Previous studies...
<p>Genes are ordered by Mann-Whitney <i>p-value (</i>** p-value<0.0001 and * p-value<0.05). Methylat...
<p>LSIL, low-grade squamous cell intraepithelial lesion; HSIL, high-grade squamous cell intraepithel...
Summary statistics for case/control expression differences in whole blood for genes identified in DN...
<p>(A) Distribution of the percentage methylation levels (shown as <i>Z</i> scores) in all tumors. B...
<p>There is a bimodal distribution of the DNA index with peaks around 1, and close to 2.</p
<p>The genes are ranked by outlier score. Spearman's coefficient was calculated to evaluate DNA meth...
<p>List of the top 10 genes that were hypermethylated in at least 85% of benign and malignant tumor ...
Cervical cancer is the fourth most common cancer affecting women worldwide, with a high incidence an...
Cervical cancer is the fourth most common cancer affecting women worldwide, with a high incidence an...
<p>All 997 genes (circles) that were deregulated in cervical cancer (CC) tumors compared to the cont...
<p>Genomic distribution of probes differentially methylated between leukemic and control samples wit...
<p>(<b>A</b>) Probability density function (PDF) distribution for methylation difference between DS ...
<p><b>A.</b> Genes commonly methylated in >95% of all samples.</p><p><b>B.</b> Genes methylated in a...
Background: Epigenetic gene silencing is one of the major causes of carcinogenesis. Its widespread o...