TBSS (Tract-Based Spatial Statistics) resulted in significant differences in FA values at the pons of the brainstem between the INS group and the controls (seen in orange) (N = 6) (row 1) using an ROI at the pons.

<p>FA value reduction were seen at the pons and culmen (rows 2 and 3) using an ROI at the cerebellum and brainstem for INS group. Significant reduction in MD were also seen at the thalamus (row 4) using an ROI at the cortex for INS group. Image orientation and display labels are in radiological convention. P<0.05 for all analyses.