Tract-based spatial statistics (TBSS) results.

<p>Results show decreases in fractional anisotropy (FA) in the multiple brain areas of persons with T2DM. Significant TBSS results (red-yellow, <i>P</i><0.05, family-wise error corrected) in sagittal, coronal, and axial views overlaid onto the group averaged FA skeleton (green) and the MNI152 T1 template. The coordinates represent the peak between-group difference in each cluster. At the peaks, negative associations were found between FA value and the blood glucose levels as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0157268#pone.0157268.g003" target="_blank">Fig 3</a>.