<p>This relationship is predicted to be dependent on the underlying proportion of ‘resistant’ infections in the study population. The relationships for underlying proportions ‘resistant’ of 0.1 (green), 0.5 (blue), and 0.9 (purple) are shown. The shaded areas represent the 50%, 80%, 90%, and 95% prediction intervals (from dark to light shading, respectively).</p
At the beginning of treatment the population consists of the sensitive strain at its carrying capaci...
<p>Two hypotheses on increased fitness in resistant parasites are compared in three panels A, B, C. ...
The carriage time is set to zero if the resistant subpopulation did not survive antibiotic treatment...
<p>A: cumulative incidence (total number of symptomatic cases) over a 28-year simulation as a functi...
(A) FOI as a function of the fraction of the susceptibles to primary and secondary infections for ch...
<p>Points correspond to the mean over 10<sup>4</sup> simulations, error-bars correspond to the 95% c...
a) Median model fits to the 7-day moving average of daily confirmed case data, along with short-term...
For each accepted particle, the process was simulated again, and the total number of infected indivi...
<p>This prediction is plotted with a 10% threshold for the percentage of patients positive on day-3 ...
<p>Boxplots show distribution of times to emergence (resistance at a level of 5% of total infecteds)...
<p>The black diamonds show the probability that any one of the resistant strains emerges (reaches a ...
<p>Monthly numbers of laboratory-confirmed influenza cases (circles) and model predictions: median (...
<p>The straight gray lines show the actual emergence timing, and the dashed line shows the timing wh...
<p><b>A</b> The model-derived clearance time distribution is shown as a function of varying immune c...
<p>Points correspond to the mean over 10<sup>4</sup> simulations, error-bars correspond to the 95% c...
At the beginning of treatment the population consists of the sensitive strain at its carrying capaci...
<p>Two hypotheses on increased fitness in resistant parasites are compared in three panels A, B, C. ...
The carriage time is set to zero if the resistant subpopulation did not survive antibiotic treatment...
<p>A: cumulative incidence (total number of symptomatic cases) over a 28-year simulation as a functi...
(A) FOI as a function of the fraction of the susceptibles to primary and secondary infections for ch...
<p>Points correspond to the mean over 10<sup>4</sup> simulations, error-bars correspond to the 95% c...
a) Median model fits to the 7-day moving average of daily confirmed case data, along with short-term...
For each accepted particle, the process was simulated again, and the total number of infected indivi...
<p>This prediction is plotted with a 10% threshold for the percentage of patients positive on day-3 ...
<p>Boxplots show distribution of times to emergence (resistance at a level of 5% of total infecteds)...
<p>The black diamonds show the probability that any one of the resistant strains emerges (reaches a ...
<p>Monthly numbers of laboratory-confirmed influenza cases (circles) and model predictions: median (...
<p>The straight gray lines show the actual emergence timing, and the dashed line shows the timing wh...
<p><b>A</b> The model-derived clearance time distribution is shown as a function of varying immune c...
<p>Points correspond to the mean over 10<sup>4</sup> simulations, error-bars correspond to the 95% c...
At the beginning of treatment the population consists of the sensitive strain at its carrying capaci...
<p>Two hypotheses on increased fitness in resistant parasites are compared in three panels A, B, C. ...
The carriage time is set to zero if the resistant subpopulation did not survive antibiotic treatment...