Gene expression patterns of OGR1 family after inhibition of PKA or PKCε activity.

<p>Mice received intraplantar injection with 25 μl CFA (A), with pre-injection with PKAI (B) or post-injection with PKCεI 1 day after CFA injection (C). At 90 min and 4 and 24 h after CFA injection or at 90 min after the second injection, mice were killed. RNA was obtained from lumbar 4–6 DRG ipsilateral and contralateral to injected paws for RT-PCR. The expression of each gene on the ipsilateral DRG was normalized to mGAPDH expression, then represented as relative expression to contralateral controls (fold change in expression). Data are mean±SEM of triplicate measurements (n = 3 mice). **p<0.01 compared to saline-injected group by one-way ANOVA with a post-hoc Bonferroni test. ##p<0.01, ###p<0.001 compared to CFA-injected group by one-way ANOVA with a post-hoc Bonferroni test.