<p>Cells were treated for 24 h at 37°C with increasing concentrations of (A) NE, or (B) LPS. The level of activation was detected by SEAP activity as measured by absorbance at 650 nm normalized to the relative number of viable cells remaining after the 24 h treatment assessed by XTT (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0126120#pone.0126120.s004" target="_blank">S4 Fig</a>). (Abbreviations CPC (C), Tween80 (W80), DODAC (D), P188 (P18), P407 (P4)).</p
<p>(A-B), Peritoneal macrophages were isolated from LPS-challenged mice, recovered overnight and re-...
<p>Mouse peritoneal macrophages were incubated with vehicle, Ber (2.0 µM), Ber (2.0 µM)+Y (5.0 µM) o...
<p>Raw264.7 macrophages pretreated for 2 hr with: 1 & 2) DMSO control; 3) rac-2-Ethoxy-3 octadecanam...
<p>(A) Macrophages were treated or not with compound <b>1</b> (25 μM) and stimulated with LPS (100 n...
<p>These cells were derived from RAW 264.7 macrophages and contain a secreted embryonic alkaline pho...
<p>(<b>A</b>) RAW 264.7 macrophages or (<b>B</b>) J774A.1 macrophages (both 5 × 10<sup>5</sup>/ml; 1...
<p>(A) Cells were treated with 0.5, 5 and 15 μM 4'-HW for 1 h prior to stimulation with LPS (100 ng/...
<p>After incubation with Sch A and Sch B for 6 h, RAW264.7 macrophages were challenged with LPS (1 μ...
<p>(<b>A</b>) THP-1 cells were infected with <i>MTB</i> H37Rv for 4 and 8 days with or without BAY, ...
<p>(A) THP-1 cells, (B) MDM, or (C) AM were pretreated with 0.1% (v/v) DMSO (open squares) or 5 µM B...
<p>(A) THP-1 XBlue™ cells were differentiated with PMA for 72h and the medium was changed for severa...
<p>M-CSF differentiated macrophages derived from unselected human CD16<sup>+/−</sup> monocytes (M0) ...
<p>Results were considered significant at §: <i>p</i> < 0.05, *: <i>p</i> < 0.01, and #: <i>p</i> < ...
<p>(<b>A</b>) Monocytes THP.R01F were differentiated into macrophages (MTHP.R01F) and DCs (DTHP.R01F...
<p>The HEK-Blue hTLR4 cells were stimulated with LPS from <i>B</i>. <i>pseudomallei</i> K96243, 1026...
<p>(A-B), Peritoneal macrophages were isolated from LPS-challenged mice, recovered overnight and re-...
<p>Mouse peritoneal macrophages were incubated with vehicle, Ber (2.0 µM), Ber (2.0 µM)+Y (5.0 µM) o...
<p>Raw264.7 macrophages pretreated for 2 hr with: 1 & 2) DMSO control; 3) rac-2-Ethoxy-3 octadecanam...
<p>(A) Macrophages were treated or not with compound <b>1</b> (25 μM) and stimulated with LPS (100 n...
<p>These cells were derived from RAW 264.7 macrophages and contain a secreted embryonic alkaline pho...
<p>(<b>A</b>) RAW 264.7 macrophages or (<b>B</b>) J774A.1 macrophages (both 5 × 10<sup>5</sup>/ml; 1...
<p>(A) Cells were treated with 0.5, 5 and 15 μM 4'-HW for 1 h prior to stimulation with LPS (100 ng/...
<p>After incubation with Sch A and Sch B for 6 h, RAW264.7 macrophages were challenged with LPS (1 μ...
<p>(<b>A</b>) THP-1 cells were infected with <i>MTB</i> H37Rv for 4 and 8 days with or without BAY, ...
<p>(A) THP-1 cells, (B) MDM, or (C) AM were pretreated with 0.1% (v/v) DMSO (open squares) or 5 µM B...
<p>(A) THP-1 XBlue™ cells were differentiated with PMA for 72h and the medium was changed for severa...
<p>M-CSF differentiated macrophages derived from unselected human CD16<sup>+/−</sup> monocytes (M0) ...
<p>Results were considered significant at §: <i>p</i> < 0.05, *: <i>p</i> < 0.01, and #: <i>p</i> < ...
<p>(<b>A</b>) Monocytes THP.R01F were differentiated into macrophages (MTHP.R01F) and DCs (DTHP.R01F...
<p>The HEK-Blue hTLR4 cells were stimulated with LPS from <i>B</i>. <i>pseudomallei</i> K96243, 1026...
<p>(A-B), Peritoneal macrophages were isolated from LPS-challenged mice, recovered overnight and re-...
<p>Mouse peritoneal macrophages were incubated with vehicle, Ber (2.0 µM), Ber (2.0 µM)+Y (5.0 µM) o...
<p>Raw264.7 macrophages pretreated for 2 hr with: 1 & 2) DMSO control; 3) rac-2-Ethoxy-3 octadecanam...