Cardiac histopathological changes in NZB/W F1 mice fed with different dietary supplements.

<p>(A) Histopathological analysis of cardiac tissue sections with hematoxylin and eosin staining and (B) representative stained apoptotic cells of cardiac sections from NZB/W F1 mice fed with different supplementations, as obtained by TUNEL assay. (C) Percentages of apoptotic cells were calculated. Images of myocardial architecture were magnified 100 times. Bars represent number of TUNEL-positive cells as a percentage of total number of cells (10 scope field count for each mice in each group) and values are expressed as mean ±SD. * and # indicate significant differences relative to SLE and SLE + cholesterol groups, respectively. Similar results were obtained in triplicate experiments. SLE: systemic lupus erythematosus; Chol: cholesterol; GM: <i>Gentiana macrophylla</i> Pall.