<p>In each hexagonal plot, three main vertices represent Spleen, MLN, and PBMC. Genes close to one of these vertices show a strong contribution to the corresponding tissue. Genes at the center contribute approximately equally to each tissue. The inner color of each gene shows its overall rank in all tissues (Fig <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0126843#pone.0126843.g005" target="_blank">5D</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0126843#pone.0126843.g005" target="_blank">5E</a>), while the outer color represents the minimum of each gene’s three ranks in the tissues.</p
<p>Changes of expression and hubness for transcription factors and genes with tissue-specific functi...
<p>Groups of expressed genes are represented as blue circle nodes and linked to the respective enric...
<p>(A.) An overview of the manually-curated dataset of 112 tissue-selective hereditary diseases (gra...
<p>The highly loaded genes contribute more to the scores that are used for classification, and hence...
<p>In each hexagonal plot, three main vertices represent MC-, UV-, and CV-based <i>judges</i>. Genes...
Summary: Although all human tissues carry out common processes, tissues are distinguished by gene ex...
<p><b>A)</b> A connectivity network for each set of key genes determined independently for each tiss...
<p>a) Tissue-specific transcription factors (circled in blue) have higher expression levels (green) ...
<p>A transcript was classified as tissue-specific if it had an expression level in one tissue that i...
<p>The <i>x</i>-axis is the number of genes in the neighborhood (defined here as adjacent genes co-e...
Identified tissue specific MR2, their associated SEG−index and respective proportion of links with t...
<p>The tree represents the hierarchy over tissues 1–4. For each tissue and each internal node in the...
<p>(A) The ratio between the expression levels of causal genes and their paralogs across tissues. Ea...
<p>A. The tissue-distribution of hereditary diseases and their causal genes shows that diseases are ...
<p>(A) Heatmaps of 5,514 lncRNA loci (red; left) and 16,201 protein-coding loci (blue; right) based ...
<p>Changes of expression and hubness for transcription factors and genes with tissue-specific functi...
<p>Groups of expressed genes are represented as blue circle nodes and linked to the respective enric...
<p>(A.) An overview of the manually-curated dataset of 112 tissue-selective hereditary diseases (gra...
<p>The highly loaded genes contribute more to the scores that are used for classification, and hence...
<p>In each hexagonal plot, three main vertices represent MC-, UV-, and CV-based <i>judges</i>. Genes...
Summary: Although all human tissues carry out common processes, tissues are distinguished by gene ex...
<p><b>A)</b> A connectivity network for each set of key genes determined independently for each tiss...
<p>a) Tissue-specific transcription factors (circled in blue) have higher expression levels (green) ...
<p>A transcript was classified as tissue-specific if it had an expression level in one tissue that i...
<p>The <i>x</i>-axis is the number of genes in the neighborhood (defined here as adjacent genes co-e...
Identified tissue specific MR2, their associated SEG−index and respective proportion of links with t...
<p>The tree represents the hierarchy over tissues 1–4. For each tissue and each internal node in the...
<p>(A) The ratio between the expression levels of causal genes and their paralogs across tissues. Ea...
<p>A. The tissue-distribution of hereditary diseases and their causal genes shows that diseases are ...
<p>(A) Heatmaps of 5,514 lncRNA loci (red; left) and 16,201 protein-coding loci (blue; right) based ...
<p>Changes of expression and hubness for transcription factors and genes with tissue-specific functi...
<p>Groups of expressed genes are represented as blue circle nodes and linked to the respective enric...
<p>(A.) An overview of the manually-curated dataset of 112 tissue-selective hereditary diseases (gra...