Time-dependent changes in candidate biomarker gene expression.

<p>The figure shows hierarchical clustering of the top 5 up-regulated DEGs on each day for each metal. When the same gene was one of the top genes for a different day of the same metal the next highest up-regulated gene was included for that day. The values shown in the heat map are the log_<b>2</b> ratio of change of the genes compared to the unexposed controls.