Quercetin combined with 2-ME inhibited proliferation and promoted apoptosis in PC-3 and LNCaP xenograft tumor tissues.

<p>(A, D) Immunohistochemical detection showed Ki67 and caspase-3 positive cells in both PC-3 and LNCaP xenograft tumor. Number of Ki67 (B, C) and caspase-3(E, F) positive cells were represented as means ± SD, number was from three random high powered fields per slide (light microscopy, hpf, 400×). *P<0.05 compared to control, #P<0.05 denotes a significant difference between combination treatment group and quercetin treated group, ※P<0.05 denotes a significant difference between combination treatment group and 2-ME treated group.