Quercetin combined with 2-ME enhanced inhibition of PC-3 xenograft tumor growth.

<p>(A) PC-3 xenograft tumors were smaller in Que or 2-ME treatment group than vehicle control, and the inhibition was more remarkable in Que and 2-ME co-treatment group. Tumor weight (B) and tumor volume (C) were reduced significantly by combination therapy, more obvious than Que or 2-ME alone. There was no significant difference in mouse weight between groups (D). Data are represented as means ± SD. *P<0.05 compared with control, #P<0.05 denotes a significant difference between combination treatment group and quercetin treated group, ※P<0.05 denotes a significant difference between combination treatment group and 2-ME treated group.