Colitogenic activity of <i>E</i>. <i>faecalis</i> is associated with infiltration of different immune cell subsets in monoassociated IL-10-/- mice.

<p>(A) Representative images of distal colon sections from IL-10-/- mice monoassociated with <i>E</i>. <i>faecalis</i> OG1RF stained by immunofluorescence for F4/80+ (red), Ly6G+ (red), CD11c+ (red) or CD3+ (red) cells, E-cadherin (intracellular domain, green), nuclei (blue) and magnifications of respective images as indicated by white frames (scale bar = 100μm). (B) Relationship between F4/80+, Ly6G+, CD11c+ or CD3+ cells infiltrating the distal colon of monoassociated IL-10-/- mice with respective histological scoring for distal colon was assessed by Pearson correlation coefficient test (F4/80+ cells: Pearson r = 0.6460, ***p<0.001; Ly6G+ cells: Pearson r = 0.7382, ****p<0.0001; CD11c+ cells: Pearson r = -0.05360, p>0.05; CD3+ cells: Pearson r = 0.6661, ***p<0.001).