<p>IL-10<sup>−/−</sup> mice were infected with different amounts of <i>C. jejuni</i> (10<sup>2</sup>, 10<sup>4</sup>, and 10<sup>6</sup> cfu/mouse) for 14 days. (A) The degree of intestinal inflammation was determined by histological analysis of colonic sections as described. (B) Representative section of the colon of IL-10<sup>−/−</sup> mice infected with 10<sup>2</sup> bacteria. n = 5 per group, magnification 100x.</p
<p>Gnotobiotic IL-10<sup>−/−</sup> mice were generated by antibiotic treatment and orally infected e...
<p>(A) Histological analysis of H&E stained colon clearly demonstrates that mice lacking both GC-C a...
The intestinal microbiota is a critical component of mucosal health as evidenced by the fact that al...
<p>Conventionally colonized 6-months-old IL-10<i><sup>−</sup></i><sup>/<i>−</i></sup> mice with chro...
<p>Gnotobiotic IL-10<sup>−/−</sup> mice were generated by antibiotic treatment and orally infected e...
<p>Gnotobiotic IL-10<sup>−/−</sup> (B10 background) as well as TLR-2<sup>−/−</sup> IL-10<sup>−/−</su...
We evaluated whether a simplified humanmicrobiota consortium (SIHUMI) induces colitis in germfree (G...
<p>Gnotobiotic IL-10<sup>−/−</sup>; NF-κB<sup>EGFP</sup> mice and control IL-10<sup>wt/wt</sup>; NF-...
<p>WT and IL-10 KO mice (n = 20) were analyzed for colonic MPO (<b>A</b>), H & E stained colon (<b>B...
We evaluated whether a simplified human microbiota consortium (SIHUMI) induces colitis in germfree (...
IL-10 is a regulatory cytokine that plays a major role in the homeostasis of the gut and this is ill...
In the healthy gut, interleukin-10 receptor (IL-10R) signaling maintains immunologic tolerance to mi...
<p>Gnotobiotic IL-10<sup>−/−</sup> mice were generated by antibiotic gut decontamination and peroral...
<p>Gnotobiotic IL-10<sup>-/-</sup> mice were generated by antibiotic treatment and perorally coloniz...
Human inflammatory bowel disease (IBD) is a chronic intestinal disease where the resident microbiota...
<p>Gnotobiotic IL-10<sup>−/−</sup> mice were generated by antibiotic treatment and orally infected e...
<p>(A) Histological analysis of H&E stained colon clearly demonstrates that mice lacking both GC-C a...
The intestinal microbiota is a critical component of mucosal health as evidenced by the fact that al...
<p>Conventionally colonized 6-months-old IL-10<i><sup>−</sup></i><sup>/<i>−</i></sup> mice with chro...
<p>Gnotobiotic IL-10<sup>−/−</sup> mice were generated by antibiotic treatment and orally infected e...
<p>Gnotobiotic IL-10<sup>−/−</sup> (B10 background) as well as TLR-2<sup>−/−</sup> IL-10<sup>−/−</su...
We evaluated whether a simplified humanmicrobiota consortium (SIHUMI) induces colitis in germfree (G...
<p>Gnotobiotic IL-10<sup>−/−</sup>; NF-κB<sup>EGFP</sup> mice and control IL-10<sup>wt/wt</sup>; NF-...
<p>WT and IL-10 KO mice (n = 20) were analyzed for colonic MPO (<b>A</b>), H & E stained colon (<b>B...
We evaluated whether a simplified human microbiota consortium (SIHUMI) induces colitis in germfree (...
IL-10 is a regulatory cytokine that plays a major role in the homeostasis of the gut and this is ill...
In the healthy gut, interleukin-10 receptor (IL-10R) signaling maintains immunologic tolerance to mi...
<p>Gnotobiotic IL-10<sup>−/−</sup> mice were generated by antibiotic gut decontamination and peroral...
<p>Gnotobiotic IL-10<sup>-/-</sup> mice were generated by antibiotic treatment and perorally coloniz...
Human inflammatory bowel disease (IBD) is a chronic intestinal disease where the resident microbiota...
<p>Gnotobiotic IL-10<sup>−/−</sup> mice were generated by antibiotic treatment and orally infected e...
<p>(A) Histological analysis of H&E stained colon clearly demonstrates that mice lacking both GC-C a...
The intestinal microbiota is a critical component of mucosal health as evidenced by the fact that al...