Bone volume fraction of regenerated bone in 10%- 50% defects at two months post-operation.

<p>The 20% defect is the same one illustrated in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0130819#pone.0130819.g002" target="_blank">Fig 2</a>. Top, red dashed lines show the cross-section level in the center of the 10% and 20% defects (A, B) and the 40% and 50% defects (C, D) where the measurements were taken. Both 10% and 20% defects regenerated a high volume fraction of bone, whereas there was much less regeneration in the 40% defects, and minimal regeneration in the 50% defects, which only regenerated at the cut ends of the fibula.