Neural STAT1 expression is critical for controlling HSV-1 replication <i>in vivo</i>.

<p>Viral titers in the TG, brain stem and brain of Stat1^N-/- or Stat1^fl/fl mice infected via corneal scarification with 2 x 10⁶ PFU/eye WT (strain 17) or Δγ34.5 virus. Viral titers were measured at 3 dpi (A) and 5 dpi (B). Dashed lines represent the limit of detection. Error bars represent SEM of a minimum of 13 mice total over 2 experiments. Two-way ANOVA was performed where ** p<0.01, ***p<0.001.