<p>Representatively, six mice from each group were killed at day 5 post infection. Primary infected eyes were homogenized and inspected for viral loads using a standard plaque assay. Statistical analysis was undertaken with a nonparametric ANOVA test. Comparisons were considered significant at *<i>P</i> < 0.05. Error bars represent the SEM.</p
<p>On Day 70, naïve or live-0ΔNLS-immunized wild-type and μMT mice were challenged with 200,000 pfu ...
<p>Groups of mice (n = 10) were infected by the intravaginal route with a single dose (ranging from ...
<p>On Day 70, naïve or live-0ΔNLS-immunized mice were challenged with 200,000 pfu per eye of HSV-2 M...
<p>Ocular disease scores of infected mice for blepharitis, epithelial defects and corneal opacity (s...
<p>The clinical disease scores of infected mice for blepharitis, epithelial defects and corneal opac...
<p>The reduced virus titers correlate with reduced anti-HSV immune responses. The total numbers of c...
<p>(A) Serum SeV-specific IgG levels measured 1 day before challenge. The data are representative of...
<p>Viral titers in the TG, brain stem and brain of Stat1<sup>N-/-</sup> or Stat1<sup>fl/fl</sup> mic...
<p>Lymphocytes derived from spleens or DLNs (R = ipsilateral, L = contralateral) of HSV-1 KOS infect...
<p><b>(A)</b> Percentage of reactivating ipsilateral or contralateral trigeminal ganglia from HSV‑1 ...
<p>(<b>A</b>) Schematic representation of the murine ocular HSV-2 infection model. Both corneas of a...
<p>A. Vero cells were seeded in a 24-well plate and infected with increasing concentrations (MOI fro...
<p>Sera from vaccinated mice were evaluated for neutralizing antibodies by plaque inhibition assay. ...
Mice were ocularly infected with HSV-1 as described above and viral titers were measured in the eye ...
<p>On Day 70, mock-, UV-0ΔNLS-, or live-0ΔNLS-immunized C57BL/10 mice were challenged with 70,000 pf...
<p>On Day 70, naïve or live-0ΔNLS-immunized wild-type and μMT mice were challenged with 200,000 pfu ...
<p>Groups of mice (n = 10) were infected by the intravaginal route with a single dose (ranging from ...
<p>On Day 70, naïve or live-0ΔNLS-immunized mice were challenged with 200,000 pfu per eye of HSV-2 M...
<p>Ocular disease scores of infected mice for blepharitis, epithelial defects and corneal opacity (s...
<p>The clinical disease scores of infected mice for blepharitis, epithelial defects and corneal opac...
<p>The reduced virus titers correlate with reduced anti-HSV immune responses. The total numbers of c...
<p>(A) Serum SeV-specific IgG levels measured 1 day before challenge. The data are representative of...
<p>Viral titers in the TG, brain stem and brain of Stat1<sup>N-/-</sup> or Stat1<sup>fl/fl</sup> mic...
<p>Lymphocytes derived from spleens or DLNs (R = ipsilateral, L = contralateral) of HSV-1 KOS infect...
<p><b>(A)</b> Percentage of reactivating ipsilateral or contralateral trigeminal ganglia from HSV‑1 ...
<p>(<b>A</b>) Schematic representation of the murine ocular HSV-2 infection model. Both corneas of a...
<p>A. Vero cells were seeded in a 24-well plate and infected with increasing concentrations (MOI fro...
<p>Sera from vaccinated mice were evaluated for neutralizing antibodies by plaque inhibition assay. ...
Mice were ocularly infected with HSV-1 as described above and viral titers were measured in the eye ...
<p>On Day 70, mock-, UV-0ΔNLS-, or live-0ΔNLS-immunized C57BL/10 mice were challenged with 70,000 pf...
<p>On Day 70, naïve or live-0ΔNLS-immunized wild-type and μMT mice were challenged with 200,000 pfu ...
<p>Groups of mice (n = 10) were infected by the intravaginal route with a single dose (ranging from ...
<p>On Day 70, naïve or live-0ΔNLS-immunized mice were challenged with 200,000 pfu per eye of HSV-2 M...