<p>Administration of tamoxifen at 0.05 mg/g body weight for 3 days also introduces robust tdTomato expression in <i>Myh6</i><sup><i>MerCreMer/+</i></sup>;<i>R26R</i><sup><i>tdTomato/+</i></sup> mouse hearts (A,B). No recombination occurs in the control hearts (<i>R26R</i><sup><i>tdTomato/+</i></sup>, C,D). Arrows in A,B indicate coronary vessels.</p
<p>Embryos of the indicated age carrying either the TCre (<b>A</b>) or TCreERT2 transgenes (<b>B–M</...
<p>Whole heart homogenates were prepared from iRyR2<sup>flox/flox</sup> (A) and iRyR2<sup>flox/Ex3-d...
Tamoxifen (Tam), a selective estrogen receptor modulator, is in wide clinical use for the treatment ...
<p><i>R26R</i><sup><i>tdTomato/+</i></sup> reporter line was used to trace <i>Myh6</i> lineage after...
<p>X-gal staining revealed robust β-galactosidase expression in the embryonic and postnatal hearts (...
<p>Very few X-gal positive cells were detected on <i>Myh6</i><sup><i>MerCreMer/+</i></sup>;<i>R26R</...
Cardiac myocyte targeted MerCreMer transgenic mice expressing tamoxifen-inducible Cre driven by the ...
<p>Mer<sup>+</sup>MyD88flox<sup>+/+</sup>, Mer<sup>-/-</sup>MyD88flox<sup>+/-</sup> and MerCreMer<su...
<p><b>A</b>, Experimental Timeline. All animals were injected with tamoxifen then sacrificed either ...
The Cre-LoxP technology, including the tamoxifen (TAM) inducible MerCreMer (MCM), is increasingly us...
<p>(A) Generation of CreLacZ mice. CAG-CAT-LacZ mice were crossbred with the MerCreMer strain in whi...
<p><i>Tcf21</i><sup><i>iCre/+</i></sup>, <i>ApoE</i><sup><i>-/-</i></sup> mice were administered tam...
<p>(A) Scheme of tamoxifen injections. 6 week old <i>Crif <sup>f/f</sup></i> (<i>Crif1<sup>WT</sup><...
Inducible and tissue-specific gene inactivation in mice has become a powerful tool to bypass embryon...
In the article1 referred to in Drs McLean and Oudit’s letter,2 we ana lyzed the effects of inactivat...
<p>Embryos of the indicated age carrying either the TCre (<b>A</b>) or TCreERT2 transgenes (<b>B–M</...
<p>Whole heart homogenates were prepared from iRyR2<sup>flox/flox</sup> (A) and iRyR2<sup>flox/Ex3-d...
Tamoxifen (Tam), a selective estrogen receptor modulator, is in wide clinical use for the treatment ...
<p><i>R26R</i><sup><i>tdTomato/+</i></sup> reporter line was used to trace <i>Myh6</i> lineage after...
<p>X-gal staining revealed robust β-galactosidase expression in the embryonic and postnatal hearts (...
<p>Very few X-gal positive cells were detected on <i>Myh6</i><sup><i>MerCreMer/+</i></sup>;<i>R26R</...
Cardiac myocyte targeted MerCreMer transgenic mice expressing tamoxifen-inducible Cre driven by the ...
<p>Mer<sup>+</sup>MyD88flox<sup>+/+</sup>, Mer<sup>-/-</sup>MyD88flox<sup>+/-</sup> and MerCreMer<su...
<p><b>A</b>, Experimental Timeline. All animals were injected with tamoxifen then sacrificed either ...
The Cre-LoxP technology, including the tamoxifen (TAM) inducible MerCreMer (MCM), is increasingly us...
<p>(A) Generation of CreLacZ mice. CAG-CAT-LacZ mice were crossbred with the MerCreMer strain in whi...
<p><i>Tcf21</i><sup><i>iCre/+</i></sup>, <i>ApoE</i><sup><i>-/-</i></sup> mice were administered tam...
<p>(A) Scheme of tamoxifen injections. 6 week old <i>Crif <sup>f/f</sup></i> (<i>Crif1<sup>WT</sup><...
Inducible and tissue-specific gene inactivation in mice has become a powerful tool to bypass embryon...
In the article1 referred to in Drs McLean and Oudit’s letter,2 we ana lyzed the effects of inactivat...
<p>Embryos of the indicated age carrying either the TCre (<b>A</b>) or TCreERT2 transgenes (<b>B–M</...
<p>Whole heart homogenates were prepared from iRyR2<sup>flox/flox</sup> (A) and iRyR2<sup>flox/Ex3-d...
Tamoxifen (Tam), a selective estrogen receptor modulator, is in wide clinical use for the treatment ...