Cardiac hypertrophy in the D2 strain.

<p>As detected by RNA-seq, β-MHC, α1-actin, ANP and BNP mRNA levels were significantly elevated in D2 mice compared to B6 mice (panels A-D). RNA-seq data on ANP and α1-actin were validated by qPCR (panel E). Western blot analysis further revealed that β-MHC protein levels in the D2 strain were significantly greater than the B6 strain (panel F).