mRNA expression levels of ANP, BNP, and β-MHC in left myocardium.

<p><b><i>A.</i></b> Relationship between mRNA expression levels and running activities in DCM mice. Upper left: ANP; upper right: BNP; bottom: β-MHC. Dotted line with gray bar is mean±SD of expression in WT myocardium. <b><i>B.</i></b> Relation of LW/BW ratio to expression of ANP (left), BNP (middle), and β-MHC (right) in DCM mice. <b><i>C</i></b><b>.</b> Relation of HW/BW ratio to ANP (left), BNP (middle), and β-MHC levels (right). All data in <b><i>A–C</i></b> were obtained from the same set of DCM mice. In <b><i>B</i></b> and <b><i>C</i></b>, HI: open circles (<i>n</i> = 12); LO: filled circles (<i>n</i> = 8); intermittent: crosses (<i>n</i> = 2). Lines indicate the least-squares fit for all DCM mice including HI, LO, and intermittent.