DhL induced cell cycle arrest in D384 cells.

<p>Cell cycle analysis. D384 cells were exposed to 0 (C-, control), 5, 7.5 and 10 μM of DhL for 6, 16 and 32 h. The fraction of cells in the G1, S, and G2/M-phases of the cell cycle was then analyzed using a FACSCanto II flow cytometer. Data were acquired and analyzed using DIVA software. A representative histogram is shown for each DhL concentration. Data represent the mean ± SEM, n = 4. Symbols denote statistically significant differences: * p<0.01 and ** p<0.001 with respect to control conditions for G2/M phase and ++ p< 0.001 with respect to control conditions for S phase.