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Pharmacodynamic profile showing ADP induced platelet aggregation over time according to treatment arms.

Tobias Geisler (320237)
Jean Booth (789357)
Elli Tavlaki (709367)
Athanasios Karathanos (320334)
Karin Müller (620362)
Michal Droppa (709365)
Meinrad Gawaz (320341)
Monica Yanez-Lopez (789358)
Simon J. Davidson (789359)
Rod H. Stables (789360)
Winston Banya (789361)
Azfar Zaman (789362)
Marcus Flather (789363)
Miles Dalby (789364)

Publication date

August 2015

DOI

10.1371/journal.pone.0135037.g003

Abstract

<p>Pharmacodynamic profile showing ADP induced platelet aggregation over time according to treatment arms.</p

Extracted data

Related items

The effect of platelet activation by different concentrations of ADP (1–100 μM) on intraplatelet [Ca<sup>2+</sup>]<sub>i</sub> dynamics over time.

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June 2015

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FEATURES OF THE COURSE OF THE DISEASE IN PATIENCE WITH CHRONIC HEART FAILURE RESISTANT TO ADP-INDUCED PLATELET AGGREGATION

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Correlation of ADP-induced aggregation in platelet rich plasma pre-treated with PGE1 or with P2Y1 inhibitor.

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Representative ADP aggregation curves demonstrating the effect of clopidogrel treatment.

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ADP induced aggregation continously decreases in washed platelets after preparation.

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<p>Platelet Aggregation Rate Induced by AA (Compound Danshen Dripping Pill +ASP vs ASP, ASP: Aspirin...

Effect of incremental concentrations of ADP on platelet aggregation in the presence of PJ34.

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<p>Platelet aggregation was induced by 5 µM (A) and 20 µM ADP (B) in the platelet rich plasma of con...

Effect of PJ34 on both phases of ADP-induced platelet aggregation.

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<p>(A) ADP concentration (1.5 to 5 µM) was determined for each donor to produce a biphasic aggregati...

Probing ADP Induced Aggregation Kinetics During Platelet-Nanoparticle Interactions : Functional Dynamics Analysis to Rationalize Safety and Benefits

Bandyopadhyay, Souvik K.
Azharuddin, Mohammad
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Ganguli, Bhaswati
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Patra, Hirak Kumar
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January 2019

Platelets, one of the most sensitive blood cells, can be activated by a range of external and intern...

Aspirin therapy does not influence the P2Y12 specific ADP(PGE1) platelet aggregation test.

Zsuzsa Bagoly (429210)
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July 2013

<p>ADP-induced aggregation in PGE1 pre-treated platelet rich plasma of controls (solid circles) and ...

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Renate Koppensteiner (58819)
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June 2015

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Alice Assinger (593678)
Ivo Volf (717873)
Diethart Schmid (717874)

April 2015

<p><b>(A)</b> Time course of time-averaged FL1-fluorescence. <b>(B)</b> Time course of time-averaged...

Indicators of ADP-induced platelet aggregation in patients with hypertension complicated by ischemic hemisphere stroke

V. V. Syvolap
S. P. Zhemanyuk

October 2017

Arterial hypertension is one of the most significant factor in the development of cardio-vascular co...

Effects of PI3K and AKT inhibitors on ADP-induced platelet aggregation.

M. Elisa Lopes-Pires (796502)
Ana C. Antunes Naime (796503)
Nádia J. Almeida Cardelli (796504)
Débora J. Anjos (796505)
Edson Antunes (93656)
Sisi Marcondes (299572)

September 2015

<p>Washed platelets (1.2 x 10<sup>8</sup> platelets/ml) were incubated with wortmannin (100 nM), LY2...

Correlations of adenosine diphosphate (ADP)-induced platelet aggregation and activation.

Thomas Gremmel (711292)
Renate Koppensteiner (58819)
Simon Panzer (711296)

June 2015

<p><b>(A)</b> Scatter plot showing ADP-induced platelet reactivity by light transmission aggregometr...

FEATURES OF THE COURSE OF THE DISEASE IN PATIENCE WITH CHRONIC HEART FAILURE RESISTANT TO ADP-INDUCED PLATELET AGGREGATION

Alyavi A.L., Khojanova Sh.I., Reymbaeva. A.A., Jabbarov A.A., Makhsudova M.X., Saydaliev R.S., Qodirova SH.A., Tursunova L.D

January 2023

The close relationship between the processes of atherogenesis and thrombosis makes it pathogenetical...

Correlation of ADP-induced aggregation in platelet rich plasma pre-treated with PGE1 or with P2Y1 inhibitor.

Zsuzsa Bagoly (429210)
Ferenc Sarkady (429211)
Tünde Magyar (429212)
János Kappelmayer (429213)
Endre Pongrácz (429214)
László Csiba (429215)
László Muszbek (429216)

July 2013

<p>Platelet rich plasma was pre-treated with 0.31 µM PGE1 or 1 mM adenosine 3’, 5’-diphosphate (A3P5...

Representative ADP aggregation curves demonstrating the effect of clopidogrel treatment.

Zsuzsa Bagoly (429210)
Ferenc Sarkady (429211)
Tünde Magyar (429212)
János Kappelmayer (429213)
Endre Pongrácz (429214)
László Csiba (429215)
László Muszbek (429216)

July 2013

<p>Platelet aggregation was performed on PGE1 pretreated (right side) and non-pretreated (left side)...

ADP induced aggregation continously decreases in washed platelets after preparation.

Juergen Koessler (847843)
Stephanie Hermann (847844)
Katja Weber (847845)
Angela Koessler (847846)
Sabine Kuhn (5666575)
Markus Boeck (847847)
Anna Kobsar (847848)

January 2016

<p>Light transmission aggregometry induced with 10 μM ADP was measured in washed platelets (3 x 10<s...

Platelet Aggregation Rate Induced by AA (Compound Danshen Dripping Pill +ASP vs ASP, ASP: Aspirin 100mg/d).

Hanyu Chen (2735152)
Zhengjie Shen (2735146)
Jiandong Chen (220306)
Haowen Zhang (2735149)
Xiaohu Chen (597584)

May 2016

<p>Platelet Aggregation Rate Induced by AA (Compound Danshen Dripping Pill +ASP vs ASP, ASP: Aspirin...

Effect of incremental concentrations of ADP on platelet aggregation in the presence of PJ34.

Marie Lechaftois (647302)
Elise Dreano (647303)
Bruno Palmier (526036)
Isabelle Margaill (647304)
Catherine Marchand-Leroux (52611)
Christilla Bachelot-Loza (619097)
Dominique Lerouet (647305)

October 2014

<p>Human PRP samples were pre-incubated with PJ34 or its vehicle and then stimulated with ADP. Resul...

Results of ADP-induced platelet aggregation.

Zsuzsa Bagoly (429210)
Ferenc Sarkady (429211)
Tünde Magyar (429212)
János Kappelmayer (429213)
Endre Pongrácz (429214)
László Csiba (429215)
László Muszbek (429216)

July 2013

<p>Platelet aggregation was induced by 5 µM (A) and 20 µM ADP (B) in the platelet rich plasma of con...

Effect of PJ34 on both phases of ADP-induced platelet aggregation.

Marie Lechaftois (647302)
Elise Dreano (647303)
Bruno Palmier (526036)
Isabelle Margaill (647304)
Catherine Marchand-Leroux (52611)
Christilla Bachelot-Loza (619097)
Dominique Lerouet (647305)

October 2014

<p>(A) ADP concentration (1.5 to 5 µM) was determined for each donor to produce a biphasic aggregati...

Probing ADP Induced Aggregation Kinetics During Platelet-Nanoparticle Interactions : Functional Dynamics Analysis to Rationalize Safety and Benefits

Bandyopadhyay, Souvik K.
Azharuddin, Mohammad
Dasgupta, Anjan K.
Ganguli, Bhaswati
SenRoy, Sugata
Patra, Hirak Kumar
Deb, Suryyani

January 2019

Platelets, one of the most sensitive blood cells, can be activated by a range of external and intern...

Aspirin therapy does not influence the P2Y12 specific ADP(PGE1) platelet aggregation test.

Zsuzsa Bagoly (429210)
Ferenc Sarkady (429211)
Tünde Magyar (429212)
János Kappelmayer (429213)
Endre Pongrácz (429214)
László Csiba (429215)
László Muszbek (429216)

July 2013

<p>ADP-induced aggregation in PGE1 pre-treated platelet rich plasma of controls (solid circles) and ...

Correlations of adenosine diphosphate (ADP)-induced platelet reactivity by light transmission aggregometry (LTA), the VerifyNow P2Y<sub>12</sub> assay, and multiple electrode aggregometry (MEA) with ADP-induced P-selectin expression and activated glycoprotein (GP) IIb/IIIa.

Thomas Gremmel (711292)
Renate Koppensteiner (58819)
Simon Panzer (711296)

June 2015

<p>Correlations of adenosine diphosphate (ADP)-induced platelet reactivity by light transmission agg...

The effect of platelet activation by different concentrations of ADP (1–100 μM) on intraplatelet [Ca<sup>2+</sup>]<sub>i</sub> dynamics over time.

Alice Assinger (593678)
Ivo Volf (717873)
Diethart Schmid (717874)

April 2015

<p><b>(A)</b> Time course of time-averaged FL1-fluorescence. <b>(B)</b> Time course of time-averaged...

Indicators of ADP-induced platelet aggregation in patients with hypertension complicated by ischemic hemisphere stroke

V. V. Syvolap
S. P. Zhemanyuk

October 2017

Arterial hypertension is one of the most significant factor in the development of cardio-vascular co...

Effects of PI3K and AKT inhibitors on ADP-induced platelet aggregation.

M. Elisa Lopes-Pires (796502)
Ana C. Antunes Naime (796503)
Nádia J. Almeida Cardelli (796504)
Débora J. Anjos (796505)
Edson Antunes (93656)
Sisi Marcondes (299572)

September 2015

<p>Washed platelets (1.2 x 10<sup>8</sup> platelets/ml) were incubated with wortmannin (100 nM), LY2...