Correlations of adenosine diphosphate (ADP)-induced platelet aggregation and activation.

<p><b>(A)</b> Scatter plot showing ADP-induced platelet reactivity by light transmission aggregometry (LTA; x-axis) vs. platelet reactivity by the VerifyNow P2Y₁₂ assay (y-axis). Circles represent individual measurements. Cut-off values for high on-treatment residual platelet reactivity are indicated by the dotted lines. PRU, P2Y₁₂ Reaction Units. <b>(B)</b> Scatter plot showing ADP-induced platelet surface P-selectin expression (x-axis) vs. ADP-induced activated glycoprotein (GP) IIb/IIIa (y-axis). Circles represent individual measurements. Cut-off values for high P-selectin and high GPIIb/IIIa are indicated by the dotted lines. <b>(C)</b> Scatter plot showing platelet reactivity by the VerifyNow P2Y₁₂ assay (x-axis) vs. ADP-induced activated glycoprotein (GP) IIb/IIIa (y-axis). Circles represent individual measurements. Cut-off values for high on-treatment residual platelet reactivity and high GPIIb/IIIa are indicated by the dotted lines. PRU, P2Y₁₂ Reaction Units.