<p>(A) Timeline, (B) Generation of chimeric mice: Bone marrow derived cells (BMDC) were isolated from a donor mouse (GFPWT) and transplanted to an irradiated recipient mouse (either WT or TLR4-/-). Following 5 weeks of consumption of water with antibiotics (AB), peripheral blood was drawn and FACS analysis performed confirming that >90% of circulating blood cells expressed GFP.</p
<p>UCB derived CD34<sup>+</sup> cells from three different HLA-A2/HA-1<sup>H</sup> donors were incub...
<p><b>A</b>) Overview of the experimental protocol. <i>HI</i>, <i>FNA</i> and <i>Tx</i> denote focal...
<p>(A) The schematic indicates the experimental procedure for determination of the re-population pot...
<p>Lane 1: MW Marker. Lanes 3: Control irradiated mouse given Lin<sup>−</sup> bone marrow cells by t...
The generation of radiation chimeras allows researchers to substitute the hematopoietic system of a ...
<p>Blood chimerism was assessed by flow cytometry 8 weeks following transplantation of GFP<sup>+/-</...
<p>Experiment was initiated as before, after 7 months of transplantation mice were subjected to seco...
<p>(A) Schematic drawings of the experimental strategies to test for recombination events in blood c...
<p>(<b>A</b>) Schematic of experimental design. Chimeric animals were established from adoptive tran...
<p>(A) Provides a diagram outlining the procedures in this experiment. BM from B6.SJL-<i>Ptprc</i><s...
<p>PCR performed with GFP specific forward (5′-AAG TTC ATC TGC ACC ACC G- 3′) and reverse (5′-TCC TT...
Schematic showing the experimental setup used to generate the data used in this article. Bone marrow...
Bone marrow (BM) cells are considered the source of stem cells for various organs. However, how quic...
<p>A, C57BL/6 mice (B6.SJL-<i>Ptprc<sup>a</sup> Pepc<sup>b</sup></i>/BoyJ ) expressing CD45.1 alloan...
<p>(A) Numbers of bone marrow cells isolated from mice receiving vector, Syk, TEL-Syk KD and TEL-Syk...
<p>UCB derived CD34<sup>+</sup> cells from three different HLA-A2/HA-1<sup>H</sup> donors were incub...
<p><b>A</b>) Overview of the experimental protocol. <i>HI</i>, <i>FNA</i> and <i>Tx</i> denote focal...
<p>(A) The schematic indicates the experimental procedure for determination of the re-population pot...
<p>Lane 1: MW Marker. Lanes 3: Control irradiated mouse given Lin<sup>−</sup> bone marrow cells by t...
The generation of radiation chimeras allows researchers to substitute the hematopoietic system of a ...
<p>Blood chimerism was assessed by flow cytometry 8 weeks following transplantation of GFP<sup>+/-</...
<p>Experiment was initiated as before, after 7 months of transplantation mice were subjected to seco...
<p>(A) Schematic drawings of the experimental strategies to test for recombination events in blood c...
<p>(<b>A</b>) Schematic of experimental design. Chimeric animals were established from adoptive tran...
<p>(A) Provides a diagram outlining the procedures in this experiment. BM from B6.SJL-<i>Ptprc</i><s...
<p>PCR performed with GFP specific forward (5′-AAG TTC ATC TGC ACC ACC G- 3′) and reverse (5′-TCC TT...
Schematic showing the experimental setup used to generate the data used in this article. Bone marrow...
Bone marrow (BM) cells are considered the source of stem cells for various organs. However, how quic...
<p>A, C57BL/6 mice (B6.SJL-<i>Ptprc<sup>a</sup> Pepc<sup>b</sup></i>/BoyJ ) expressing CD45.1 alloan...
<p>(A) Numbers of bone marrow cells isolated from mice receiving vector, Syk, TEL-Syk KD and TEL-Syk...
<p>UCB derived CD34<sup>+</sup> cells from three different HLA-A2/HA-1<sup>H</sup> donors were incub...
<p><b>A</b>) Overview of the experimental protocol. <i>HI</i>, <i>FNA</i> and <i>Tx</i> denote focal...
<p>(A) The schematic indicates the experimental procedure for determination of the re-population pot...