Mean viral loads in A129 mice after infection with 10⁴ PFU of wild-type CHIKV, or the 181/clone25 or CHIKV/IRES vaccine candidate strains delivered in the footpad.

<p>The limit of detection of the plaque assays was 60 PFU/g or ml. Data were analyzed by one-way ANOVA with a Bonferroni post hoc test for pairwise comparisons.