Antibody responses induced by vaccine strain 181/25 and 37997-mCherry.

<p>Anti-CHIKV (left) and anti-mCherry (right) total IgG antibody titers in surviving IFNαR-/- mice (A) at 3 weeks after CHIKV 181/25 and CHIKV 37997-mCherry infection and (B) at 11 days post-challenge with CHIKV LR were measured by end-point ELISA. The dashed lines indicate the detection limits. Statistical significance was determined by ANOVA with a Sidak’s multiple comparisons test (*P<0.0332; **P<0.0021; ***p<0.0002) (n = 3–5).