Ingenuity Pathway Analysis of proteins that were significantly altered after 12-h EBR treatment in LNCaP cells.

<p>A) Red, up-regulated proteins; green, significantly downregulated proteins; white, proteins known to be in the network but not identified in our study. The color depth indicates the magnitude of the change in protein expression levels. The shapes are indicative of the molecular class (i.e., protein family). B) IPA showing the pathways might involve in EBR-induced cellular alterations, <b>C.</b> tunicamycin, as an anticancer agent causing a similar effect. Lines connecting the molecules indicate molecular relationships. The arrow styles indicate specific molecular relationships and the directionality of the interaction. Reprinted from Ingenuity Pathways Analysis under a CC BY license, with permission from QIAGEN Silicon Valley, original copyright 2000–2013.