<p>Times in the top row are in days (d), weeks (w) or year (yr) after spinal cord transection (TX). Ctrl, control; Tot, total; IHC, immunohistochemistry; MO, morpholino antisense oligonucleotide. In the 4-week experiment, a single dye (DAF 488, green) was applied to a complete TX 4 weeks after, and 1 cm caudal to an unlabeled hemisection (hemi-TX) to look for axon collaterals crossing the midline. In the 5-week experiment, one dye (DMTR, red) was applied to a hemisection, and then 4 weeks later, a second dye (DAF 488, green) was applied to a complete TX 1 cm caudally.</p><p>Numbers of animals used for each experiment.</p
<p>Thoracic spinal cord sections were subjected to Bielchowsky silver stains for axons. A section fr...
<p>Animals received a dorsal column transection or a sham lesion at T7 or C4 level and survived eigh...
<p>Longitudinal spinal cord sections from the control (A, D), 50 U (B, E) and 100 U (C, F) ChABC-tre...
<p>(A–C) Reconstruction of hindlimb CST collaterals (black) from 5 consecutive sections in the cervi...
<p>Stereological estimation of numbers of myelinated axons at the centre, 2 mm rostral and 2 mm caud...
<p><b>A,</b> unilateral labeling of previously uninjured axons in a wholemounted spinal cord rostral...
<p><b>A.</b> Representative images of transversely cut cryosections of spinal cords stained with Hoe...
<p>Upper panel: (A) Tiled images taken of the thoraco-lumbar segments of a spinal cord from a spinal...
BackgroundSpinal cord injury (SCI) is a debilitating event with multiple mechanisms of degeneration ...
<p><b>A-B</b>. Representative electron micrographs of ventral hemi-spinal cords of DMSO- or Mtz-trea...
<p>TX-Only: (A) Camera lucida tracing of 5-HT immunoreactive fibers in a TX-only animal. (B) 5-HT an...
(A-D) Bright field images showing a fixed, unstained control lamprey spinal cord (A) and transected ...
<p><b>A</b>) Number of NeuN immunoreactive nuclei per section (mean ± SEM) in 10 mm segments centred...
<p>The spinal cord was cut between 8<sup>th</sup> and 9<sup>th</sup> vertebra. At different time poi...
<p>(A,B) Confocal images of contacts (arrows, defined as boutons in apposition to neuronal cell bodi...
<p>Thoracic spinal cord sections were subjected to Bielchowsky silver stains for axons. A section fr...
<p>Animals received a dorsal column transection or a sham lesion at T7 or C4 level and survived eigh...
<p>Longitudinal spinal cord sections from the control (A, D), 50 U (B, E) and 100 U (C, F) ChABC-tre...
<p>(A–C) Reconstruction of hindlimb CST collaterals (black) from 5 consecutive sections in the cervi...
<p>Stereological estimation of numbers of myelinated axons at the centre, 2 mm rostral and 2 mm caud...
<p><b>A,</b> unilateral labeling of previously uninjured axons in a wholemounted spinal cord rostral...
<p><b>A.</b> Representative images of transversely cut cryosections of spinal cords stained with Hoe...
<p>Upper panel: (A) Tiled images taken of the thoraco-lumbar segments of a spinal cord from a spinal...
BackgroundSpinal cord injury (SCI) is a debilitating event with multiple mechanisms of degeneration ...
<p><b>A-B</b>. Representative electron micrographs of ventral hemi-spinal cords of DMSO- or Mtz-trea...
<p>TX-Only: (A) Camera lucida tracing of 5-HT immunoreactive fibers in a TX-only animal. (B) 5-HT an...
(A-D) Bright field images showing a fixed, unstained control lamprey spinal cord (A) and transected ...
<p><b>A</b>) Number of NeuN immunoreactive nuclei per section (mean ± SEM) in 10 mm segments centred...
<p>The spinal cord was cut between 8<sup>th</sup> and 9<sup>th</sup> vertebra. At different time poi...
<p>(A,B) Confocal images of contacts (arrows, defined as boutons in apposition to neuronal cell bodi...
<p>Thoracic spinal cord sections were subjected to Bielchowsky silver stains for axons. A section fr...
<p>Animals received a dorsal column transection or a sham lesion at T7 or C4 level and survived eigh...
<p>Longitudinal spinal cord sections from the control (A, D), 50 U (B, E) and 100 U (C, F) ChABC-tre...