The circadian profiles of MEFs derived from WT, <i>Bmal1</i>^{<i>+/GTΔC</i>}, <i>Bmal1</i>^{<i>GTΔC/GTΔC</i>}, <i>Bmal1</i>^<i>+/-</i> and <i>Bmal1</i>^<i>-/-</i> mice.

<p><b>(A)</b> The representative real-time luminescence profiles of each genotype. Cells were synchronized by 2hr treatment of DEX and monitored by the real-time bioluminescence device. (B) FRP of WT, <i>Bmal1</i>^{<i>+/GTΔC</i>} and <i>Bmal1</i>^<i>+/-</i> cells. Asterisks indicate significant differences (*<i>p</i><0.05) compared with WT mice. Data are represented as the mean ± S.E.M. (n = 3).