Connectivity of intramodular hub genes in three selected gene co-expression modules.

<p>A) Highly connected genes in the brown module. B) Highly connected genes in the turquoise module. C) Highly connected genes in the yellow module. The node shapes indicate gene biotype, hexagon = antisense, octagon = lincRNA, circle = protein-coding, rounded rectangle = pseudogene, and rectangle = sense overlapping. The connectivity of a gene is encoded in node size with bigger nodes meaning higher connectivity. Edge transparency and width encode gene pair adjacencies, with thicker lines and lower transparency meaning higher similarity.