<p><sup>1</sup>SNP with strongest metabolite association is presented in <b>bold</b> while SNP with strongest eQTL was marked with an asterisk<b>*</b></p><p><sup>2</sup>Gene with strongest association is presented in <b>bold</b></p><p><sup>3</sup>A q-value<5% was considered as significant, i.e. FDR is controlled at 5%.</p><p><sup>4</sup>These genes are located on the same chromosome as the lead-SNPs at distances larger than 1Mb</p><p>Results of eQTL analysis of validated loci.</p
Genome-wide association studies (GWASs) have shown a large number of genetic variants to be associat...
BACKGROUND: Identification of single nucleotide polymorphisms (SNPs) associated with gene expression...
AbstractGenome-wide association studies (GWASs) have shown a large number of genetic variants to be ...
<p>Table displays significant associations of eQTL genes and metabolites for validated loci. Genes a...
<p>Table includes all validated loci of our analysis. Validation is based on either successful repli...
<p>Metabolite linkages that exceeded the 0.1 FDR significance threshold are plotted based on their m...
<p>Note: N/A:not available; “Score”: −log10 (P); LCLs: lymphoblastoid cell lines; transcript-QTL: tr...
Expression quantitative trait loci (eQTLs) are genetic markers associated with transcription of Ribo...
We identified proximal and distal target genes for 145 genome-wide significant metabolite-associated...
Disease-associated SNPs on chromosome 22 were tested for eQTL associations using GTEx analysis (v7) ...
Gene expression quantitative trait locus (eQTL) mapping has become a powerful tool in systems biolog...
<p>The forest plot shows the genetic effects of SNP rs7207370 with respect to the expression levels ...
<p>Number of significant genes, methylation sites or assayable heterozygous sites in fibroblasts (F)...
<p>In plot <b>A</b>, the result was summarized according to the involved genes (RefSeq mRNAs). In pl...
<p><i>Positions are given according to NCBI 36.3 genome build. SNPs were assigned to genes within 60...
Genome-wide association studies (GWASs) have shown a large number of genetic variants to be associat...
BACKGROUND: Identification of single nucleotide polymorphisms (SNPs) associated with gene expression...
AbstractGenome-wide association studies (GWASs) have shown a large number of genetic variants to be ...
<p>Table displays significant associations of eQTL genes and metabolites for validated loci. Genes a...
<p>Table includes all validated loci of our analysis. Validation is based on either successful repli...
<p>Metabolite linkages that exceeded the 0.1 FDR significance threshold are plotted based on their m...
<p>Note: N/A:not available; “Score”: −log10 (P); LCLs: lymphoblastoid cell lines; transcript-QTL: tr...
Expression quantitative trait loci (eQTLs) are genetic markers associated with transcription of Ribo...
We identified proximal and distal target genes for 145 genome-wide significant metabolite-associated...
Disease-associated SNPs on chromosome 22 were tested for eQTL associations using GTEx analysis (v7) ...
Gene expression quantitative trait locus (eQTL) mapping has become a powerful tool in systems biolog...
<p>The forest plot shows the genetic effects of SNP rs7207370 with respect to the expression levels ...
<p>Number of significant genes, methylation sites or assayable heterozygous sites in fibroblasts (F)...
<p>In plot <b>A</b>, the result was summarized according to the involved genes (RefSeq mRNAs). In pl...
<p><i>Positions are given according to NCBI 36.3 genome build. SNPs were assigned to genes within 60...
Genome-wide association studies (GWASs) have shown a large number of genetic variants to be associat...
BACKGROUND: Identification of single nucleotide polymorphisms (SNPs) associated with gene expression...
AbstractGenome-wide association studies (GWASs) have shown a large number of genetic variants to be ...