<p>Number of significant genes, methylation sites or assayable heterozygous sites in fibroblasts (F), LCLs (L) and T-cells (T). The association analyses on eQTL, mQTLs and eQTMs were previously reported [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004958#pgen.1004958.ref037" target="_blank">37</a>].</p><p>* FDR calculated as number of expected over number of observed based on the nominal P-value threshold.</p><p>Summary of associations and allele-specific expression analyses in GenCord.</p
The aetiology and pathophysiology of complex diseases are driven by the interaction between genetic ...
<p>(A) List of genes potentially associated with aberrant methylation patterns in DLBCL. Boxplots vi...
The aetiology and pathophysiology of complex diseases are driven by the interaction between genetic ...
<p>(A) Number of all significant positive (pos-eQTMs) and negative (neg-eQTMs) correlations between ...
<p>Table displays significant associations of eQTL genes and metabolites for validated loci. Genes a...
<p>For each regulatory phenotype we randomly sampled a matched number of SNPs, within 3 kb of a DNA ...
<p><b>A)</b> QQ plot of –log10 p-values for testing the null of no association between eQTL SNPs and...
<p>Effect sizes of expression Quantitative Trait Locus (eQTL) (A) and methylation QTLs (mQTL) (B) un...
<p>(A) Functional annotation analysis of commonly methylated or unmethylated gene promoters in all t...
<p>Panel A shows the GD association of 67 genotyped and 972 imputed SNPs in the GWAS samples. The co...
Most genetic variants identified in genome-wide association studies (GWAS) of complex traits are tho...
Most genetic variants identified in genome-wide association studies (GWASs) of complex traits are th...
<p>Expression was taken as the response variable, with one of mean -score, mean derivative and methy...
(A) Methylation ratio of CpG site 7 of STXBP6 grouped by lung cancer stage. (B) Methylation ratios o...
<p>Applying the new systems genetics approach for <i>trans</i>-eQTL identification in RA CD4+ T cell...
The aetiology and pathophysiology of complex diseases are driven by the interaction between genetic ...
<p>(A) List of genes potentially associated with aberrant methylation patterns in DLBCL. Boxplots vi...
The aetiology and pathophysiology of complex diseases are driven by the interaction between genetic ...
<p>(A) Number of all significant positive (pos-eQTMs) and negative (neg-eQTMs) correlations between ...
<p>Table displays significant associations of eQTL genes and metabolites for validated loci. Genes a...
<p>For each regulatory phenotype we randomly sampled a matched number of SNPs, within 3 kb of a DNA ...
<p><b>A)</b> QQ plot of –log10 p-values for testing the null of no association between eQTL SNPs and...
<p>Effect sizes of expression Quantitative Trait Locus (eQTL) (A) and methylation QTLs (mQTL) (B) un...
<p>(A) Functional annotation analysis of commonly methylated or unmethylated gene promoters in all t...
<p>Panel A shows the GD association of 67 genotyped and 972 imputed SNPs in the GWAS samples. The co...
Most genetic variants identified in genome-wide association studies (GWAS) of complex traits are tho...
Most genetic variants identified in genome-wide association studies (GWASs) of complex traits are th...
<p>Expression was taken as the response variable, with one of mean -score, mean derivative and methy...
(A) Methylation ratio of CpG site 7 of STXBP6 grouped by lung cancer stage. (B) Methylation ratios o...
<p>Applying the new systems genetics approach for <i>trans</i>-eQTL identification in RA CD4+ T cell...
The aetiology and pathophysiology of complex diseases are driven by the interaction between genetic ...
<p>(A) List of genes potentially associated with aberrant methylation patterns in DLBCL. Boxplots vi...
The aetiology and pathophysiology of complex diseases are driven by the interaction between genetic ...