List of all mutations. This file shows all mutations passing thresholds as explained in “Methods”. The column “confirmed” shows mutations that have been confirmed by either Sanger Sequencing or deep whole exome sequencing in another research project (unpublished data). The column “included in analysis” shows the mutations that passed our threshold for putative driver mutations, based on effect, SIFT, polyphen scores and COSMIC (see “Methods”). The column “dubious” shows the mutations that might be dubious based on gene length, expression or replication time [20]. (XLSX 64 kb
Validation of TTK, TP53BP2 and genome-wide copy number profiles with Nimblegen 135Â K aCGH arrays. a...
Clinical and treatment characteristics of the 18 cases with no ctDNA alterations detected. Table S2....
Figure S3. DNA copy number alterations in the IBC cohort. The genes with DNA copy number alterations...
Specific mutations within affected pathways. This file shows all pathways with KEGG IDs, and mutatio...
Association between mutations and chemotherapy response or relapse. This table shows the top five ge...
Table S4. Significantly mutated gene test by MuSiC2. TP53 and FANCC were shown to have the highest n...
1977 Cancer Gene Panel. This file lists all 1,977 genes in the Cancer Gene Panel, used in this study...
Table S3. Driver gene analysis by MutSig. The two genes with q value <â10â3 (TP53 and FANCC, hig...
Heatmap of all copy number aberrations in the dataset. Samples are represented by rows, genomic regi...
Table S2. Pathogenic and likely pathogenic mutations identified in the studied cohort. Annotations a...
Figure S1. Comparison of somatic mutation frequency between IBC and non-IBC in four subgroups. (a) T...
Comparison of top alterations listed by Balko et al. (reference [30]) (A) and our study (B) for TCGA...
INTRODUCTION: In triple negative breast cancers (TNBC) the initial response to chemotherapy is often...
BRCA1 gene expression, measured by RT-PCR, for BRCA1-methylated, mutated and non-mutated/non-methyla...
The comparison of mutation rates for top mutated genes and 14 pathway genes. The mutation rates for ...
Validation of TTK, TP53BP2 and genome-wide copy number profiles with Nimblegen 135Â K aCGH arrays. a...
Clinical and treatment characteristics of the 18 cases with no ctDNA alterations detected. Table S2....
Figure S3. DNA copy number alterations in the IBC cohort. The genes with DNA copy number alterations...
Specific mutations within affected pathways. This file shows all pathways with KEGG IDs, and mutatio...
Association between mutations and chemotherapy response or relapse. This table shows the top five ge...
Table S4. Significantly mutated gene test by MuSiC2. TP53 and FANCC were shown to have the highest n...
1977 Cancer Gene Panel. This file lists all 1,977 genes in the Cancer Gene Panel, used in this study...
Table S3. Driver gene analysis by MutSig. The two genes with q value <â10â3 (TP53 and FANCC, hig...
Heatmap of all copy number aberrations in the dataset. Samples are represented by rows, genomic regi...
Table S2. Pathogenic and likely pathogenic mutations identified in the studied cohort. Annotations a...
Figure S1. Comparison of somatic mutation frequency between IBC and non-IBC in four subgroups. (a) T...
Comparison of top alterations listed by Balko et al. (reference [30]) (A) and our study (B) for TCGA...
INTRODUCTION: In triple negative breast cancers (TNBC) the initial response to chemotherapy is often...
BRCA1 gene expression, measured by RT-PCR, for BRCA1-methylated, mutated and non-mutated/non-methyla...
The comparison of mutation rates for top mutated genes and 14 pathway genes. The mutation rates for ...
Validation of TTK, TP53BP2 and genome-wide copy number profiles with Nimblegen 135Â K aCGH arrays. a...
Clinical and treatment characteristics of the 18 cases with no ctDNA alterations detected. Table S2....
Figure S3. DNA copy number alterations in the IBC cohort. The genes with DNA copy number alterations...