<p>(Panels A and B). TH immunostaining of eye sections of WT (A) and APC<sup>Min</sup> mice (B), showing decreased TH in the sub retinal space of APC<sup>Min</sup> mice. The nucleus was counterstained with 4, 6-diamidino-2-phenylindole (DAPI) (blue). C, Fifty micrograms of retinal protein was used for western blot analysis of TH. D, Protein levels were semiquantified with densitometry, normalized by β-actin levels, and compared between APC<sup>Min</sup> mice and WT mice littermates (mean ± SD, n = 5), ** <i>P</i>< 0.01.</p
<p>A) <i>Top</i>: Representative blots of syntaxin-I and β-tubulin in retinas of wild-type and rd1 m...
<p>(A) H&E and safranin staining of 5 μm sagittal sections of eyecups of young (3-month-old) and age...
<p>Dark-reared <i>rd10</i> mice were treated with AAV5-XIAP by sub-retinal injection at age P4 or P2...
<p>H&E stained cross-sections show that the RPE membrane (arrows) is broken and the retina is thicke...
<p>(<b>A–H</b>) Immunostaining of β-catenin (red) and GS (green) in the retina of the diabetic <i>β-...
<p>Retinal fundus images of a three month old WT (A) and Hdc<sup>−/−</sup> mouse (B) retina. No lesi...
Background: The rd1 mouse retina displays fast degeneration of photoreceptors resulting in a depleti...
<p><b>A</b>). mRNA level of SOD2, SOD1, and catalase in the RPE was determined by real time RT-PCR (...
<p>Note: ↑: the protein level is up-regulated in the untreated <i>rd12</i> retinas; ↓: the protein l...
<p>A, B) Representative images of vertical sections of adult wild-type (A) and rd1 (B) mouse retinas...
<p>Normal retina morphology was seen in WT mice (A), while the retina appeared disrupted in these mi...
<p>Anti-HCN1 antibodies were used to immunostain retina from <i>A)</i> wild type <i>B)</i> TRIP8b 1b...
<p><b>A</b>). XBP1 expression in the RPE in XBP1 KO and littermate WT mice. The single layer of RPE ...
<p>APOE4 mice at the age of 18–20 months were fed a high fat, cholesterol enriched diet (HFC) for 2 ...
<p>A) Representative blots of synaptophysin and β-tubulin in whole retinas of wild-type and rd1 mice...
<p>A) <i>Top</i>: Representative blots of syntaxin-I and β-tubulin in retinas of wild-type and rd1 m...
<p>(A) H&E and safranin staining of 5 μm sagittal sections of eyecups of young (3-month-old) and age...
<p>Dark-reared <i>rd10</i> mice were treated with AAV5-XIAP by sub-retinal injection at age P4 or P2...
<p>H&E stained cross-sections show that the RPE membrane (arrows) is broken and the retina is thicke...
<p>(<b>A–H</b>) Immunostaining of β-catenin (red) and GS (green) in the retina of the diabetic <i>β-...
<p>Retinal fundus images of a three month old WT (A) and Hdc<sup>−/−</sup> mouse (B) retina. No lesi...
Background: The rd1 mouse retina displays fast degeneration of photoreceptors resulting in a depleti...
<p><b>A</b>). mRNA level of SOD2, SOD1, and catalase in the RPE was determined by real time RT-PCR (...
<p>Note: ↑: the protein level is up-regulated in the untreated <i>rd12</i> retinas; ↓: the protein l...
<p>A, B) Representative images of vertical sections of adult wild-type (A) and rd1 (B) mouse retinas...
<p>Normal retina morphology was seen in WT mice (A), while the retina appeared disrupted in these mi...
<p>Anti-HCN1 antibodies were used to immunostain retina from <i>A)</i> wild type <i>B)</i> TRIP8b 1b...
<p><b>A</b>). XBP1 expression in the RPE in XBP1 KO and littermate WT mice. The single layer of RPE ...
<p>APOE4 mice at the age of 18–20 months were fed a high fat, cholesterol enriched diet (HFC) for 2 ...
<p>A) Representative blots of synaptophysin and β-tubulin in whole retinas of wild-type and rd1 mice...
<p>A) <i>Top</i>: Representative blots of syntaxin-I and β-tubulin in retinas of wild-type and rd1 m...
<p>(A) H&E and safranin staining of 5 μm sagittal sections of eyecups of young (3-month-old) and age...
<p>Dark-reared <i>rd10</i> mice were treated with AAV5-XIAP by sub-retinal injection at age P4 or P2...