Additional file 9: Figure S8. of A gene expression signature identifying transient DNMT1 depletion as a causal factor of cancer-germline gene activation in melanoma

shRNA-dependent inhibition of RB1, but not of p107 and p130, induces up-regulation of ICCG genes in human fibroblasts. Microarray expression data were extracted from the GSE19864 dataset (Chicas et al., Cancer Cell, 2010, 17:376). Fold change in expression is given for the 21 ICCG genes that overlapped with the Sen set of genes (see Additional file 3: Figure S2), and corresponds to the ratio (log2) of probe intensities between the indicated condition and control cells. (PDF 3940 kb