<p>The proportion of peptides with predicted high affinity to MHCI and MHCII is significantly higher for peptides within an ordered protein domain. Boxplots represent the distribution of MHC-binding peptides across all MHC alleles tested.</p
Highly polymorphic major histocompatibility complex (MHC) molecules are at the heart of adaptive imm...
<p>MHC class I and MHC class II bind to specific TCRs on the surface of the MHC molecule that is fac...
<p>The whole-genome immunoinformatic analysis conducted on the 1754 <i>F. tularensis</i> ORF product...
Major histocompatibility complex class I (MHC I) proteins provide protection from intracellular path...
<p>IC<sub>50</sub> values are plotted as cognate wild type and variant pairs, where lower IC<sub>50<...
Background: Class II Major Histocompatibility Complex (MHC) molecules have an open-ended binding gro...
<div><p>Malaria remains a significant global health burden. The development of an effective malaria ...
<p>Abbreviations: <i>P. falciparum</i> = <i>Plasmodium falciparum</i>, <i>C. elegans</i> = <i>Ca...
<p>Peptides with both weak (<500 nM) and strong (<50 nM) predicted affinity are considered as positi...
MHC class II molecules play a fundamental role in the cellular immune system: they load short peptid...
Malaria remains a significant global health burden. The development of an effective malaria vaccine ...
For each of the three proteins FTT0814, FTT0289 and IglC, the predicted MHCII binding affinity of se...
Algorithms derived from measurements of short-peptide (8-10 mers) binding to class I MHC proteins su...
Major histocompatibility complex class I (MHC-1) molecules bind peptide fragments derived from cytos...
A key component of pathogen-specific adaptive immunity in vertebrates is the presentation of pathoge...
Highly polymorphic major histocompatibility complex (MHC) molecules are at the heart of adaptive imm...
<p>MHC class I and MHC class II bind to specific TCRs on the surface of the MHC molecule that is fac...
<p>The whole-genome immunoinformatic analysis conducted on the 1754 <i>F. tularensis</i> ORF product...
Major histocompatibility complex class I (MHC I) proteins provide protection from intracellular path...
<p>IC<sub>50</sub> values are plotted as cognate wild type and variant pairs, where lower IC<sub>50<...
Background: Class II Major Histocompatibility Complex (MHC) molecules have an open-ended binding gro...
<div><p>Malaria remains a significant global health burden. The development of an effective malaria ...
<p>Abbreviations: <i>P. falciparum</i> = <i>Plasmodium falciparum</i>, <i>C. elegans</i> = <i>Ca...
<p>Peptides with both weak (<500 nM) and strong (<50 nM) predicted affinity are considered as positi...
MHC class II molecules play a fundamental role in the cellular immune system: they load short peptid...
Malaria remains a significant global health burden. The development of an effective malaria vaccine ...
For each of the three proteins FTT0814, FTT0289 and IglC, the predicted MHCII binding affinity of se...
Algorithms derived from measurements of short-peptide (8-10 mers) binding to class I MHC proteins su...
Major histocompatibility complex class I (MHC-1) molecules bind peptide fragments derived from cytos...
A key component of pathogen-specific adaptive immunity in vertebrates is the presentation of pathoge...
Highly polymorphic major histocompatibility complex (MHC) molecules are at the heart of adaptive imm...
<p>MHC class I and MHC class II bind to specific TCRs on the surface of the MHC molecule that is fac...
<p>The whole-genome immunoinformatic analysis conducted on the 1754 <i>F. tularensis</i> ORF product...