<p>Thrombin generation was started with 0.5 pM TF and 16.7 mM CaCl<sub>2</sub>. The parameters depicted are the Peak height (A), ETP (B), Lagtime (C), Time-to-peak (D) and Velocity index (E). Data are medians with interquartile ranges.</p
<p>For approximation of TGCs with one peak, a type I Gumbel's distribution function was used (A). Th...
<p>The average thrombin concentration within a thrombus was calculated using a spatial-temporal comp...
<p>FVIII concentration for each variant was adjusted to 5 ng/ml in complete medium. Subsequently eac...
<p>Thrombin generation was started with 1 pM TF, 4 μM phospholipid vesicles and 16.7 mM CaCl<sub>2</...
<p>Thrombin generation was started with 0.5 pM TF and 16.7 mM CaCl<sub>2</sub>. The parameters depic...
<p>Data are presented as median [IQR] for lag time, normalized ETP (nETP), normalized peak height (n...
<p><b>A)</b><i>Left Axis:</i> Thrombin concentration time series showing the mean (solid black line)...
<p><b>A)</b><i>Left Axis:</i> Thrombin concentration time series showing the mean (solid black line)...
<p><b>A)</b><i>Left Axis:</i> Thrombin concentration time series showing the mean (solid black line)...
<p>Medians with interquartile ranges of thrombin generation parameters in plasma.</p
<p>Ref, reference category; 95% CI, 95% confidence interval. OR are relative to the reference catego...
<p>Thrombin generation analysis (1 pM TF) of plasma collected from 104 ACS and 42 non-ACS patients d...
<p>A computationally-simulated time course of thrombin generation with all factors at their mean phy...
<p>Before preparation of plasma, PCCs were added to undiluted (100%) and diluted (80, 60, 40, and 20...
CAT data shown include the ETF parameter, which is the area under the thrombin curve, the peak heigh...
<p>For approximation of TGCs with one peak, a type I Gumbel's distribution function was used (A). Th...
<p>The average thrombin concentration within a thrombus was calculated using a spatial-temporal comp...
<p>FVIII concentration for each variant was adjusted to 5 ng/ml in complete medium. Subsequently eac...
<p>Thrombin generation was started with 1 pM TF, 4 μM phospholipid vesicles and 16.7 mM CaCl<sub>2</...
<p>Thrombin generation was started with 0.5 pM TF and 16.7 mM CaCl<sub>2</sub>. The parameters depic...
<p>Data are presented as median [IQR] for lag time, normalized ETP (nETP), normalized peak height (n...
<p><b>A)</b><i>Left Axis:</i> Thrombin concentration time series showing the mean (solid black line)...
<p><b>A)</b><i>Left Axis:</i> Thrombin concentration time series showing the mean (solid black line)...
<p><b>A)</b><i>Left Axis:</i> Thrombin concentration time series showing the mean (solid black line)...
<p>Medians with interquartile ranges of thrombin generation parameters in plasma.</p
<p>Ref, reference category; 95% CI, 95% confidence interval. OR are relative to the reference catego...
<p>Thrombin generation analysis (1 pM TF) of plasma collected from 104 ACS and 42 non-ACS patients d...
<p>A computationally-simulated time course of thrombin generation with all factors at their mean phy...
<p>Before preparation of plasma, PCCs were added to undiluted (100%) and diluted (80, 60, 40, and 20...
CAT data shown include the ETF parameter, which is the area under the thrombin curve, the peak heigh...
<p>For approximation of TGCs with one peak, a type I Gumbel's distribution function was used (A). Th...
<p>The average thrombin concentration within a thrombus was calculated using a spatial-temporal comp...
<p>FVIII concentration for each variant was adjusted to 5 ng/ml in complete medium. Subsequently eac...