Thrombin generation parameters of FVIII variants.
- Behnaz Pezeshkpoor (4229824)
- Ursula Schreck (4229827)
- Arijit Biswas (752609)
- Julia Driesen (539613)
- Ann-Cristin Berkemeier (4229821)
- Anna Pavlova (2610877)
- Jens Müller (263387)
- Johannes Oldenburg (138185)
Publication date
July 2017
DOIAbstract
<p>FVIII concentration for each variant was adjusted to 5 ng/ml in complete medium. Subsequently each variant was diluted 1:1 in FVIII deficient plasma and triggered with 4 μM of phospholipids. The mean is calculated from three independent experiments performed in duplicate. (WT: wild-type; ETP: Endogenous thrombin potential; ttpeak: time to peak; SD: Standard deviation of mean).</p
Add to ORKG