Overall HIV-1-specific T cell responses induced throughout the study.

<p>(A) Total HIV-1-specific (Env+Gag+GPN) CD4 and CD8 T cell responses in vaccinated and placebo groups before vaccination (W0), after two (W6) or three (W18) MVA-B or placebo doses or at time of HAART interruption (W24). n values represent the number of positive Env-, Gag- and GPN-specific T cell responses at each time point. <i>p</i>-values for significant differences in the proportion of responses were determined using the χ² test for the equality of proportions. (B) Magnitude of the total HIV-1-specific (Env+Gag+GPN) CD4 and CD8 T cell responses in vaccinees and placebos pre- and post-vaccination. The boxes indicate the mean and interquartile range (IQR). <i>p</i>-values for significant differences were determined using the Wilcoxon rank sum test with continuity correction and are represented. All data are background-subtracted.