Group data (mean ± SE) from experiment 2 demonstrating the area of the SEP N₂₀–P₂₅–N₃₃ complex (upper graph) and pain (numerical rating scale; NRS; lower graph) at each time point before, during and after the hypertonic saline infusion.

<p>The dotted line represents baseline and the shaded area the duration of the hypertonic saline infusion. The area of the SEP was suppressed at block 2 during the painful infusion and remained suppressed at 25 minutes follow-up. *—P<0.05.