Photomicrographs of rat liver (H&E stain).

<p><b>(A)</b> Control liver showing normal hepatocytes arranged in cords, obvious sinusoids (s), and central vein (cv). <b>(B, C)</b> Hepatic injury induced by CCl₄. Note hepatic cells with ballooning degeneration (b), focal necrotic cell death (ne), and diffuse fatty changes (arrows) (in B). Microvesicular steatosis (i.e., accumulation of small fat droplets) in hepatocyte cytosol (arrows), and inflammatory infiltrates (arrowhead) are evident in liver tissue (in C). <b>(D)</b> CCl₄+TAU group showing an improvement of cellular structure and uniform sinusoidal arrays (compared to B). Pathological fatty deposition (arrows) and also normal centrilobular hepatocytes (h) with well-defined cell borders, dense cytoplasm and central nuclei are visible. <b>(E)</b> CCl₄+SIL group with less severe liver injury. Focal hepatocellular degeneration (d) is observed. <b>(F)</b> CCl₄+TAU+SIL group indicating no pathologic lesions.