Effects of RXR agonists on DR1/DR5 sequence transcription.
- Akiko Saito-Hakoda (841447)
- Akira Uruno (841448)
- Atsushi Yokoyama (841449)
- Kyoko Shimizu (841450)
- Rehana Parvin (841451)
- Masataka Kudo (625668)
- Takako Saito-Ito (841452)
- Ikuko Sato (841453)
- Naotaka Kogure (841454)
- Dai Suzuki (423401)
- Hiroki Shimada (720231)
- Takeo Yoshikawa (36402)
- Ikuma Fujiwara (841455)
- Hiroyuki Kagechika (838715)
- Yasumasa Iwasaki (841456)
- Shigeo Kure (318677)
- Sadayoshi Ito (431945)
- Akira Sugawara (524103)
Publication date
January 2016
DOIAbstract
<p>CV-1 cells transiently transfected with DR1-Luc reporter plasmid (DR1-Luc), RXRα-pcDNA1/Amp (RXRα), and pCMV-β-gal were incubated either without (-) or with (100 nM, 1 μM, 5 μM, or 10 μM) HX630 (A) or PA024 (B) for 48 hr. Additionally, CV-1 cells transiently transfected with DR5-Luc reporter plasmid (DR5-Luc), RXRα-pcDNA1/Amp (RXRα), pCMX-hRARα (RARα), and pCMV-β-gal were incubated either in the absence (-) or presence of 10 μM Am80 without (-) or with (100 nM, 1 μM, 5 μM, or 10 μM) HX630 (C) or PA024 (D) for 48 hr. Results are expressed as percentages of each control. Each point represents mean ± SEM (n = 4). *<i>P</i><0.05 vs control (HX630 (-) in A, PA024 (-) in B, Am80 (-) HX630 (-) in C, and Am80 (-) PA024 (-) in D).</p
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