Gene expression levels of endocrine and exocrine differentiation markers in pancreases from Atoh8 Δ^panc mice at (E)15.5.

<p>Total pancreatic RNA was prepared from Atoh8 Δ^panc and control embryos at (E)15.5. Gene expression levels were assessed by qRT-PCR as described in Methods. Values are expressed relative to control pancreases, set at 1. Expression levels for <i>Atoh8</i> and endocrine cell markers (A), endocrine differentiation transcription factors (B) and exocrine genes (C). n = 10 per genotype from 4 independent litters; mean ± SE; * p< 0.05, ** p< 0.01;, *** p< 0.001 vs Control.