Age-dependent spatial reference learning and memory impairments of 5xFAD mice.

<p>5xFAD mice demonstrated impaired learning ability to locate the hidden platform in an age-dependent manner (<b>A</b>). *P<0.05 vs other groups. (<b>B</b>) 5xFAD mice had compromised function in spatial reference memory in an age-dependent manner. *P<0.05 vs other groups. (<b>C</b>) Mice in different groups didn't show significant change in their swimming speed. N = 5–6 mice of each group.