Topological comparison between proteins in Superfamily I ([] ) and those not in a superfamily (| = |).

<p>A single established or predicted topology is included for each family, although it is possible that some families include members with more than one topology (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0152733#pone.0152733.t001" target="_blank">Table 1</a>).