Table of compound 6 K i values (3 s.f.) versus recombinant cathepsin S, K, V, L and B. (PPTX 36 kb
Additional file 1: Figure S1. Design of a novel PKA inhibitor, MHY4571, from the structure of the we...
Figure S1. Cath-D expression in different BC subtypes. Total cath-D expression was determined in 159...
The IC50 values showing the inhibitory effect of LL28 on the anchorage-dependent colony -forming abi...
MTT assay shows Compound 6 not to affect MC38 cell viability at 100 or 1000 nM. (PPTX 64 kb
Compound 6 treatment regime did not affect mouse weights during the MCF7 xenograft study, suggesting...
Analysis of MC38 tumor bearing mice serum at day 13 (24 h after compound 6 administration) revealed ...
Compound 6 treatment regime did not affect mouse weights during the MC38 syngeneic study, suggesting...
The IC50 values showing the inhibitory effect of LL28 on the viability of a panel of human lung canc...
Figure S5. Selectivity of F1 and E2 towards pro-cath-D. Indirect ELISA was performed with recombinan...
Changes in the level of GPT, BUN, and creatinine by treatment with LL28 in mice. (PDF 109Â kb
Additional file 1: Fig. S1. Tumor volume of different treatment groups on Day 10. SPESN38-5 by IV wa...
Figure S6. Biodistribution analysis of anti-cath-D F1 and E2 human antibodies. Nude mice bearing sub...
MBIC displayed synergistic effect with selected conventional drugs. A. shows isobolograms that link ...
Figure S3. Representative image of cath-D expression in TNBC biopsies. Cath-D expression was monitor...
Effect on cell survival and protein levels in HCA7 and HCT116 cells. (A) Effect of different concent...
Additional file 1: Figure S1. Design of a novel PKA inhibitor, MHY4571, from the structure of the we...
Figure S1. Cath-D expression in different BC subtypes. Total cath-D expression was determined in 159...
The IC50 values showing the inhibitory effect of LL28 on the anchorage-dependent colony -forming abi...
MTT assay shows Compound 6 not to affect MC38 cell viability at 100 or 1000 nM. (PPTX 64 kb
Compound 6 treatment regime did not affect mouse weights during the MCF7 xenograft study, suggesting...
Analysis of MC38 tumor bearing mice serum at day 13 (24 h after compound 6 administration) revealed ...
Compound 6 treatment regime did not affect mouse weights during the MC38 syngeneic study, suggesting...
The IC50 values showing the inhibitory effect of LL28 on the viability of a panel of human lung canc...
Figure S5. Selectivity of F1 and E2 towards pro-cath-D. Indirect ELISA was performed with recombinan...
Changes in the level of GPT, BUN, and creatinine by treatment with LL28 in mice. (PDF 109Â kb
Additional file 1: Fig. S1. Tumor volume of different treatment groups on Day 10. SPESN38-5 by IV wa...
Figure S6. Biodistribution analysis of anti-cath-D F1 and E2 human antibodies. Nude mice bearing sub...
MBIC displayed synergistic effect with selected conventional drugs. A. shows isobolograms that link ...
Figure S3. Representative image of cath-D expression in TNBC biopsies. Cath-D expression was monitor...
Effect on cell survival and protein levels in HCA7 and HCT116 cells. (A) Effect of different concent...
Additional file 1: Figure S1. Design of a novel PKA inhibitor, MHY4571, from the structure of the we...
Figure S1. Cath-D expression in different BC subtypes. Total cath-D expression was determined in 159...
The IC50 values showing the inhibitory effect of LL28 on the anchorage-dependent colony -forming abi...
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