Figure S1. Cath-D expression in different BC subtypes. Total cath-D expression was determined in 159 whole cytosols from primary BC biopsies (HR+/HER2+ (n = 38); HR-/HER2+ (n = 38); HR+/HER2- (n = 42); HR-/HER- (n = 41)) by sandwich ELISA with the immobilized anti-human cath-D D7E3 antibody and the anti-human cath-D M1G8 antibody coupled to HRP. HR= ER + PR. Mean ± SEM. (PPTX 61 kb
Figure S1. RTK expression and ERBB2-targeting antibody response in breast cancer cell lines. Figure ...
MDA-231 tumors retained a stable FRα expression profile after UNT, CD19 CAR, or FRα CAR T cell treat...
IHC controls. a–c, Example of control staining with secondary antibody Anti-C-Myc-Cy3 (red) alone, o...
Figure S3. Representative image of cath-D expression in TNBC biopsies. Cath-D expression was monitor...
Figure S5. Selectivity of F1 and E2 towards pro-cath-D. Indirect ELISA was performed with recombinan...
Figure S9. Binding of F1Fc to pro-cath-D secreted from MDA-MB-231 cells. Sandwich ELISA in which pro...
Figure S6. Biodistribution analysis of anti-cath-D F1 and E2 human antibodies. Nude mice bearing sub...
Figure S4. Generation of anti-cath-D human scFv fragments by phage display. (A) Enrichment of anti-c...
Table S1. Nucleotide sequences of the primers used for qPCR experiments. (PDF 163 kb
IHC analysis of human CD4-, CD3-, CD8-, CD20-, CD68-, CD4-, and CD8-positive cells present in BCM-21...
Table S1 Analysis of HLA type in PDX BCM-2147/-4913 and CD34+ HSCs. HLA typing was performed by usin...
Figure S1. Flow cytometric detection of HER3 on human breast cancer cell lines with anti-HER3 monocl...
Figure S1 Generation of a murine EMT6-hHER2 breast cancer cell line. A, Human-HER2 expression in EMT...
Table S1. Epitope mapping of HER3-VIA using spotted 15-mer peptide arrays. Epitope mapping was perfo...
Representative figure showing the results of flow cytometric analysis of human cells collected from ...
Figure S1. RTK expression and ERBB2-targeting antibody response in breast cancer cell lines. Figure ...
MDA-231 tumors retained a stable FRα expression profile after UNT, CD19 CAR, or FRα CAR T cell treat...
IHC controls. a–c, Example of control staining with secondary antibody Anti-C-Myc-Cy3 (red) alone, o...
Figure S3. Representative image of cath-D expression in TNBC biopsies. Cath-D expression was monitor...
Figure S5. Selectivity of F1 and E2 towards pro-cath-D. Indirect ELISA was performed with recombinan...
Figure S9. Binding of F1Fc to pro-cath-D secreted from MDA-MB-231 cells. Sandwich ELISA in which pro...
Figure S6. Biodistribution analysis of anti-cath-D F1 and E2 human antibodies. Nude mice bearing sub...
Figure S4. Generation of anti-cath-D human scFv fragments by phage display. (A) Enrichment of anti-c...
Table S1. Nucleotide sequences of the primers used for qPCR experiments. (PDF 163 kb
IHC analysis of human CD4-, CD3-, CD8-, CD20-, CD68-, CD4-, and CD8-positive cells present in BCM-21...
Table S1 Analysis of HLA type in PDX BCM-2147/-4913 and CD34+ HSCs. HLA typing was performed by usin...
Figure S1. Flow cytometric detection of HER3 on human breast cancer cell lines with anti-HER3 monocl...
Figure S1 Generation of a murine EMT6-hHER2 breast cancer cell line. A, Human-HER2 expression in EMT...
Table S1. Epitope mapping of HER3-VIA using spotted 15-mer peptide arrays. Epitope mapping was perfo...
Representative figure showing the results of flow cytometric analysis of human cells collected from ...
Figure S1. RTK expression and ERBB2-targeting antibody response in breast cancer cell lines. Figure ...
MDA-231 tumors retained a stable FRα expression profile after UNT, CD19 CAR, or FRα CAR T cell treat...
IHC controls. a–c, Example of control staining with secondary antibody Anti-C-Myc-Cy3 (red) alone, o...